FIGURE

Fig. 2

ID

ZDB-FIG-090804-56

Publication

Ng et al., 2009 - Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development

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Fig. 2

gart and paics mutants have pigmentation defects and microphthalmia. (A-G) Dorsal (A,B,D,E,G,H) and lateral (C,F,I) images of wild-type (A-C), gart (D-F) and paics (G-I) embryos at 5 dpf. Wild-type embryos possess xanthophore (yellow arrow), melanophore (black arrow) and iridophore (gray arrow) derived pigments. gart and paics mutants have substantially less xanthophore and iridophore pigmentation and reduced levels of melanin pigmentation. Mutants are also microphthalmic. Scale bar: 100μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gart^{hi3526bTg/hi3526bTg} paics^{hi2688Tg/hi2688Tg}
Observed In:	eye iridophore pigment granule melanocyte pigment granule pigmentation xanthophore pigment granule
Stage:	Day 5

Phenotype Detail

Acknowledgments

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