FIGURE

Fig. S5

ID
ZDB-FIG-090408-71
Publication
Borodovsky et al., 2009 - Neural protein Olig2 acts upstream of the transcriptional regulator sim1 to specify diencephalic dopaminergic neurons
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Fig. S5

Gain of function of Sim1 and Olig2 rescues the respective morphant phenotypes. High-resolution micrographs of embryos at 52 hours post fertilization (dorsal view, anterior to the left) that were immunostained with an anti-TH antibody. Diencephalic DA groups are marked. Embryos were injected with antisense morpholinos directed against either sim1 (Sim1MO; B, C) or olig2 (Olig2MO; E, F) in the absence (B,E) or presence (C,F) of HSE:Sim1/GFP or HSE:Olig2/GFP constructs. Temperature induced gene expression was performed as described in the legend for Supp. Fig. S4. Scale bar: 25 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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