FIGURE

Fig. 6

ID

ZDB-FIG-080904-16

Publication

Sperber et al., 2008 - barx1 is necessary for ectomesenchyme proliferation and osteochondroprogenitor condensation in the zebrafish pharyngeal arches

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Fig. 6

Loss of barx1 enhances chordin and gdf5 expression in the jaw joint. Whole-mount in situ hybridization for (A, B) bapx1, (C, D) chordin (chd), and (E, F) gdf5. (A, C, E) Control uninjected embryos; (B, D, F) barx1 morphants (see Fig. 4). Embryonic ages as indicated. (A, B) Lateral view, anterior to the left. (C–F) Ventral view, anterior at the top; asterisk indicates Meckel's cartilage, open arrowheads indicate jaw joint expression domains; e, eye; ch, ceratohyal; o orifice. Scale bar: (A–F) 50 μm.

Expression Data

Genes:	chrd gdf5 nkx3-2
Fish:	EKW EKW + MO1-barx1 + MO2-barx1
Knockdown Reagents:	MO1-barx1 MO2-barx1
Anatomical Terms:	ceratohyal cartilage joint mandibular arch skeleton
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	EKW + MO1-barx1 + MO2-barx1
Knockdown Reagents:	MO1-barx1 MO2-barx1
Observed In:	embryonic skeletal joint morphogenesis
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 321(1), Sperber, S.M., and Dawid, I.B., barx1 is necessary for ectomesenchyme proliferation and osteochondroprogenitor condensation in the zebrafish pharyngeal arches, 101-110, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.