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Fig. 2

ID

ZDB-FIG-070918-52

Publication

Walker et al., 2006 - Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning

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Fig. 2

The sturgeon gene is furinA. (A) sturgeon (furinA) maps to Danio rerio chromosome 7. (B) PCR genotyping illustrating co-segregation of nonsense lesion with furinA^tg419 mutant phenotype following MseI digestion. (C and D) Sequence chromatograms of furinA⁺ (wt), furinA^tg419, and furinA^b963 alleles around lesion sites in furinA. Arrows indicate lesions. (E) Schematic of protein domains in furinA⁺ (wt), furinA^tg419, and furinA^b963 alleles. Abbreviations: sp (signal peptide), pro (propeptide), cys (cysteine rich), tm (transmembrane), cyt (cytosolic).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 295(1), Walker, M.B., Miller, C.T., Talbot, J.C., Stock, D.W., and Kimmel, C.B., Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning, 194-205, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.