FIGURE

Fig. 3

ID
ZDB-FIG-070802-14
Publication
Schlueter et al., 2007 - Insulin-like growth factor receptor 1b is required for zebrafish primordial germ cell migration and survival
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Fig. 3

IGF1Rb is required for normal PGC migration. Ectopic PGCs (arrows) were detected rarely in control-MO-injected embryos (A), whereas they were frequently observed, in both somatic tissues (B) and throughout the yolk cell (C) of igf1rb-MO-injected embryos. (D) Mean numbers of ectopic PGCs in zebrafish embryos after morpholino injections, and/or overexpression of an antiapoptotic Bcl2-like protein (Bcl2l). Data represent means ± SEM, with sample size indicated in parentheses. Superscript letters denote significant differences between groups (ANOVA, Tukey's, P < 0.05). Magnification (A–C), 200x.

Expression Data
Gene:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: 20-25 somites

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In:
Stage: 20-25 somites

Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 305(1), Schlueter, P.J., Sang, X., Duan, C., and Wood, A.W., Insulin-like growth factor receptor 1b is required for zebrafish primordial germ cell migration and survival, 377-387, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.