FIGURE

Fig. 3

ID

ZDB-FIG-060825-9

Publication

Koudijs et al., 2005 - The Zebrafish Mutants dre, uki, and lep Encode Negative Regulators of the Hedgehog Signaling Pathway

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Fig. 3

Patterning of the Branchial Arches in a 5-Mo-Old dre Mutant
(A and B) The strict organization of the brachial arch into primary (p) and secondary (s) lamellae in a wild-type situation (100× magnification). Higher magnification shows stacks of single chondrocytes in the primary lamellae.
(C and D) Sectioning of a dre mutant shows disturbed patterning, resulting in the absence of secondary lamellae and the presence of foci of chondrocyte-like cells in the primary lamellae (arrowsHE, hematoxylin and eosin stain; wt, wild-type.
(E and F) Alcian Blue staining reveals the presence of differentiated chondrocytes in the wild-type (wt) primary lamellae, but not in the dre mutant, indicating that the differentiation of these chondrocytes is affected (200×).
(G and H) Branchial arches of uki and lep mutants appear to be wild-type (wt).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sufu^{tm146d/tm146d}
Observed In:	chondrocyte differentiation pharyngeal arch 3-7 chondrocyte
Stage:	Adult

Phenotype Detail

Acknowledgments

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