FIGURE

Fig. 5

ID
ZDB-FIG-050527-2
Publication
Londin et al., 2005 - Chordin, FGF signaling, and mesodermal factors cooperate in zebrafish neural induction
Other Figures
All Figure Page
Back to All Figure Page
Fig. 5

FGF signaling represses BMP transcription. Real-time PCR analysis of XFD (A and B) and Δ-FGFR-4 (C and D)-microinjected wild-type embryos during late blastula and early gastrula stages. The fold change (y-axis) of the markers bmp2, bmp4, and bmp7 is set relative to control (GFP)-injected embryos. XFD- and Δ-FGFR-4-injected embryos show an increase BMP transcript levels during late blastula stages. (E–H) RNA in situ hybridization of bmp2 expression in control (E and F)- and XFD-injected wild-type embryos (G and H). In XFD-injected embryos, the bmp2 expression domain extends into the dorsal ectoderm. Panels E and G are lateral views of shield stage embryos and F and H are animal pole views of the same embryos.

Expression Data
Genes:
Fish:
Anatomical Term:
Stage Range: Sphere to Shield

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 279(1), Londin, E.R., Niemiec, J., and Sirotkin, H.I., Chordin, FGF signaling, and mesodermal factors cooperate in zebrafish neural induction, 1-19, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.