FIGURE

Fig. 2

ID

ZDB-FIG-050513-2

Publication

Filippi et al., 2005 - The basic helix-loop-helix olig3 establishes the neural plate boundary of the trunk and is necessary for development of the dorsal spinal cord

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

olig3 controls specification of the neural crest. (a–d) The levels and the expression domains of sox10 and foxd3 are decreased in four-somite embryos injected with olig3 mRNA (b and d) (phenotype in >90% of injected embryos, n = 30). (e and f) The expression of foxd3 is increased in 15-somite embryos treated with olig3MO (f) (morphant phenotype > 90%, n = 20). Similarly, the expression of crestin is increased in 30-hpf embryos treated with olig3MO (h and f) (morphant phenotype > 90%, n = 40). Similar results are obtained in 24-hpf embryos hybridized with sox10 (k and l) (morphant phenotype > 90%, n = 30). Embryos are in dorsal (a–h, k, and l) or lateral (i and j) view, anterior to the top (a–d) or to the left (e–l).

Expression Data

Genes:	crestin foxd3 sox10
Fish:	WT WT + MO2-olig4
Knockdown Reagent:	MO2-olig4
Anatomical Terms:	mesenchyme derived from trunk neural crest neural crest peripheral nervous system
Stage Range:	14-19 somites to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA