CRISPR

CRISPR1-galcb

ID

ZDB-CRISPR-251118-4

Name

CRISPR1-galcb

Previous Names

None

Target

galcb (1)

Sequence

5' - GGCATTGGTGGATTAAGCGGTGG - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
ubx102	galcb

Expression

Gene expression in Wild Types + CRISPR1-galcb

No data available

Phenotype

Phenotype resulting from CRISPR1-galcb

No data available

Phenotype of all Fish created by or utilizing CRISPR1-galcb

Phenotype	Fish	Conditions	Figures
swimming behavior process quality, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 2 from Guerra et al., 2025
brain neu1 expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 6 from Guerra et al., 2025
brain gfap expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain decreased weight, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 1 from Guerra et al., 2025
whole organism decreased weight, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 1 from Guerra et al., 2025
diencephalon axon cytoplasm increased accumulation neuron lysosome, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
whole organism decreased length, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 1 from Guerra et al., 2025
brain myelination decreased process quality, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
whole organism sterile, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	text only from Guerra et al., 2025
brain rbfox3a expression decreased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain nes expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain asah1a expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 6 from Guerra et al., 2025
diencephalon axon degenerate, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
brain neurod1 expression decreased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain tnfa expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
diencephalon myelin sheath decreased thickness, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
diencephalon axon cytoplasm increased accumulation neuron mitochondrion, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
brain mpeg1.1 expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain gm2a expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 6 from Guerra et al., 2025
brain mpz expression decreased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
brain glb1 expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 6 from Guerra et al., 2025
brain asah1b expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 6 from Guerra et al., 2025
optic tectum myelination decreased process quality, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
brain cxcl8b.1 expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain apoeb expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain il1b expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 4 from Guerra et al., 2025
brain Ab11-mbp labeling increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 3 from Guerra et al., 2025
whole organism decreased life span, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 1 from Guerra et al., 2025
brain degs1 expression increased amount, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 6 from Guerra et al., 2025
brain galactosylceramidase activity decreased occurrence, abnormal	galcb^{ubx102/ubx102} (AB)	standard conditions	Fig. 1 from Guerra et al., 2025

Citations