CRISPR

CRISPR1-foxl1

ID

ZDB-CRISPR-230201-1

Name

CRISPR1-foxl1

Previous Names

None

Target

foxl1 (1)

Sequence

5' - AGGCATCATCCCCGCGCT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
nfl1	foxl1

Expression

Gene expression in Wild Types + CRISPR1-foxl1

No data available

Phenotype

Phenotype resulting from CRISPR1-foxl1

No data available

Phenotype of all Fish created by or utilizing CRISPR1-foxl1

Phenotype	Fish	Conditions	Figures
opercular flap ossification decreased process quality, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 4 from Hawkey-Noble et al., 2022
whole organism matn1 expression decreased amount, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 7 from Hawkey-Noble et al., 2022
ventral mandibular arch cartilage element decreased size, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 from Hawkey-Noble et al., 2022
whole organism hbae3 expression decreased amount, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 7 from Hawkey-Noble et al., 2022
ceratobranchial cartilage decreased size, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 from Hawkey-Noble et al., 2022
pharyngeal arch 2 ossification decreased process quality, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 4 from Hawkey-Noble et al., 2022
hyomandibula ossification decreased process quality, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 , Figure 2 from Hawkey-Noble et al., 2022
whole organism col1a1b expression increased amount, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 7 from Hawkey-Noble et al., 2022
hyosymplectic cartilage decreased size, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 from Hawkey-Noble et al., 2022
mandibular arch skeleton circular, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 from Hawkey-Noble et al., 2022
whole organism col1a1b expression decreased amount, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 7 from Hawkey-Noble et al., 2022
mandibular arch skeleton shortened, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 from Hawkey-Noble et al., 2022
whole organism col11a2 expression decreased amount, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 7 from Hawkey-Noble et al., 2022
whole organism hpxa expression decreased amount, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 7 from Hawkey-Noble et al., 2022
ceratohyal cartilage decreased size, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 from Hawkey-Noble et al., 2022
palatoquadrate arch cartilage element decreased size, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 from Hawkey-Noble et al., 2022
ceratohyal cartilage ossification decreased process quality, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 1 , Figure 2 from Hawkey-Noble et al., 2022
whole organism col1a1a expression decreased amount, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 7 from Hawkey-Noble et al., 2022
pharyngeal arch 1 ossification decreased process quality, abnormal	foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 4 from Hawkey-Noble et al., 2022
opercular flap ossification decreased process quality, abnormal	foxc1a^{ua1017/ua1017}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 4 from Hawkey-Noble et al., 2022
pharyngeal arch 2 ossification decreased process quality, abnormal	foxc1a^{ua1017/ua1017}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 4 from Hawkey-Noble et al., 2022
cranial cartilage ossification absent process, abnormal	foxc1a^{ua1017/ua1017}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 6 from Hawkey-Noble et al., 2022
pericardium edematous, abnormal	foxc1a^{ua1017/ua1017}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 4 from Hawkey-Noble et al., 2022
vertebra ossification absent process, abnormal	foxc1a^{ua1017/ua1017}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 6 from Hawkey-Noble et al., 2022
pharyngeal arch 1 ossification decreased process quality, abnormal	foxc1a^{ua1017/ua1017}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 4 from Hawkey-Noble et al., 2022
coelom edematous, abnormal	foxc1a^{ua1017/ua1017}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 6 from Hawkey-Noble et al., 2022
cranial cartilage ossification absent process, abnormal	foxc1b^{ua1018/ua1018}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 6 from Hawkey-Noble et al., 2022
vertebra ossification absent process, abnormal	foxc1b^{ua1018/ua1018}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 6 from Hawkey-Noble et al., 2022
coelom edematous, abnormal	foxc1b^{ua1018/ua1018}; foxl1^nfl1/nfl1 (AB)	standard conditions	Figure 6 from Hawkey-Noble et al., 2022

Citations