CRISPR

CRISPR2-lepr

ID
ZDB-CRISPR-160816-3
Name
CRISPR2-lepr
Previous Names
None
Target
Sequence
5' - GGAGCGCCAGTAAAGCCGTGTGG - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Genome Build: GRCz11Chromosome: 6
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
nz303 lepr
1 - 1 of 1
Expression
Gene expression in Wild Types + CRISPR2-lepr
No data available
Phenotype
Phenotype resulting from CRISPR2-lepr
Phenotype Fish Figures
pancreas has extra parts of type pancreatic B cell, abnormal vu513Tg + CRISPR2-lepr Fig. 3 with image from Michel et al., 2016
1 - 1 of 1
Phenotype of all Fish created by or utilizing CRISPR2-lepr
Phenotype Fish Conditions Figures
glucose homeostasis decreased process quality, abnormal leprnz303/nz303 (AB) nutrient increased Fig. 2 with image from Kamstra et al., 2022
whole organism increased length, abnormal leprnz303/nz303 (AB) nutrient increased Fig. 2 with image from Kamstra et al., 2022
glucose homeostasis decreased process quality, abnormal leprnz303/nz303 (AB) chemical treatment by injection: Leptin Fig. 4 with image from Kamstra et al., 2022
whole organism increased mass, abnormal leprnz303/nz303 (AB) nutrient increased Fig. 2 with image from Kamstra et al., 2022
blood glucose increased amount, abnormal leprnz303/nz303 (AB) chemical treatment by injection: Leptin, chemical treatment by environment: glucose Fig. 1 with image from Kamstra et al., 2022
1 - 5 of 19 Show all
Citations
TSV
1 - 2 of 2
Show
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.