Genomic Feature
hi2169Tg
- ID
- ZDB-ALT-030715-6
- Name
- hi2169Tg
- Synonyms
-
- hi2169 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the minus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 15: 16012609 - 16012610 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Exon 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| hnf1bahi2169Tg/hi2169Tg | Homozygous | ♀+/- ♂+/- | 17 figures  from 10 publications | 22 figures from 10 publications | |
| hnf1bahi2169Tg/+ | Heterozygous | ♀+/- ♂+/- | Fig. 3 from Choe et al., 2008 | ||
| hnf1bahi2169Tg/+ (AB) | Heterozygous | Unknown | |||
| hnf1bahi2169Tg | Unknown | Unknown | 2 figures from 2 publications | 6 figures from 5 publications | |
| hnf1bahi2169Tg/hi2169Tg; gz4Tg | Complex | Fig. 2 from Bagnat et al., 2007 | |||
| hnf1bahi2169Tg/hi2169Tg; gz15Tg; jh1Tg | Complex | Fig. 2 from Lancman et al., 2013 | |||
| hnf1bahi2169Tg/hi2169Tg; jh1Tg | Complex | Fig. 2 from Lancman et al., 2013 | |||
| hnf1bahi2169Tg/hi2169Tg + MO2-hnf1ba | Complex | Fig. 3 from Choe et al., 2008 | Fig. 3 from Choe et al., 2008 | ||
| hnf1bas430/+; hnf1bahi2169Tg/+; jh1Tg | Complex | Fig. 1 from Lancman et al., 2013 | |||
| hnf1bas430/+; hnf1bahi2169Tg/+; w34Tg | Complex | Fig. 5 from Lancman et al., 2013 | Fig. 5 from Lancman et al., 2013 |
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Supplemental Information
- Genotyping protocol
- hi2169tg.pdf
- Ghosh, P., Maurer, J.M., Sagerström, C.G. (2018) Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish. Neural Development. 13:13
- Lancman, J.J., Zvenigorodsky, N., Gates, K.P., Zhang, D., Solomon, K., Humphrey, R.K., Kuo, T., Setiawan, L., Verkade, H., Chi, Y.I., Jhala, U.S., Wright, C.V., Stainier, D.Y., and Dong, P.D. (2013) Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb. Development (Cambridge, England). 140(13):2669-2679
- Choe, S.K., Zhang, X., Hirsch, N., Straubhaar, J., and Sagerström, C.G. (2011) A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center. Developmental Biology. 358(2):356-67
- Liu, J., and Stainier, D.Y. (2010) Tbx5 and Bmp Signaling Are Essential for Proepicardium Specification in Zebrafish. Circulation research. 106(12):1818-1828
- Sapède, D., and Pujades, C. (2010) Hedgehog signaling governs the development of otic sensory epithelium and its associated innervation in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(10):3612-3623
- Dutton, K., Abbas, L., Spencer, J., Brannon, C., Mowbray, C., Nikaido, M., Kelsh, R.N., and Whitfield, T.T. (2009) A zebrafish model for Waardenburg syndrome type IV reveals diverse roles for Sox10 in the otic vesicle. Disease models & mechanisms. 2(1-2):68-83
- Stedman, A., Lecaudey, V., Havis, E., Anselme, I., Wassef, M., Gilardi-Hebenstreit, P., and Schneider-Maunoury, S. (2009) A functional interaction between Irx and Meis patterns the anterior hindbrain and activates krox20 expression in rhombomere 3. Developmental Biology. 327(2):566-577
- Choe, S.K., Hirsch, N., Zhang, X., and Sagerström, C.G. (2008) hnf1b genes in zebrafish hindbrain development. Zebrafish. 5(3):179-187
- Lokmane, L., Haumaitre, C., Garcia-Villalba, P., Anselme, I., Schneider-Maunoury, S., and Cereghini, S. (2008) Crucial role of vHNF1 in vertebrate hepatic specification. Development (Cambridge, England). 135(16):2777-2786
- Nakamura, M., Choe, S.K., Runko, A.P., Gardner, P.D., and Sagerström, C.G. (2008) Nlz1/Znf703 acts as a repressor of transcription. BMC Developmental Biology. 8:108
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