ZFIN Lab: Epidermal Stem Cell Lab

ZFIN ID: ZDB-LAB-100401-1

Epidermal Stem Cell Lab

PI/Director:	Hsiao, Chung-Der
Contact Person:	Hsiao, Chung-Der
Email:	cdhsiao@yahoo.com.tw
URL:	http://cdhsiao.weebly.com
Address:	Epidermal Stem Cell Lab Department of Bioscience Technology Chung Yuan Christian Univ. 200, Chung Pei Rd. Chung-Li, 32023 Taiwan
Country:	Taiwan
Phone:	886-3-2653545
Fax:	886-3-2653599
Line Designation:	cy

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 28 genomic features

STATEMENT OF RESEARCH INTERESTS

1. Development of new genome editing tools of TALEN and CRISPR to manipulate fish genome
2. Development of Zebrafish model for human diseases (Obesity, aging and genetic disorders)
3. Development of new tools and zebrafsh models suitable to perform high throughput drug screening and behavioral assay
4. Development of bioinformatic pipeline to annotate aquatic animal’s transcriptome and decode genome

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Chang, W.C., Chen, M.J., Hsiao, C.D., Hu, R.Z., Huang, Y.S., Chen, Y.F., Yang, T.H., Tsai, G.Y., Chou, C.W., Chen, R.S., Chuang, Y.J., Liu, Y.W. (2023) The anti-platelet drug cilostazol enhances heart rate and interrenal steroidogenesis and exerts a scant effect on innate immune responses in zebrafish. PLoS One. 18:e0292858e0292858

Audira, G., Huang, J.C., Chen, K.H., Kurnia, K.A., Vasquez, R.D., Roldan, M.J.M., Lai, Y.H., Hsiao, C.D., Yen, C.Y. (2023) A comprehensive painkillers screening by assessing zebrafish behaviors after caudal fin amputation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 168:115641115641

Saputra, F., Lai, Y.H., Roldan, M.J.M., Alos, H.C., Aventurado, C.A., Vasquez, R.D., Hsiao, C.D. (2023) The Effect of the Pyrethroid Pesticide Fenpropathrin on the Cardiac Performance of Zebrafish and the Potential Mechanism of Toxicity. Biology. 12(9):

Balitaan, J.N.I., Luo, W.J., Su, Y.W., Yu, C.Y., Wu, T.Y., Chang, C.A., Jia, H.W., Lin, S.R., Hsiao, C.D., Yeh, J.M. (2023) Healing Wounds Efficiently with Biomimetic Soft Matter: Injectable Self-Healing Neutral Glycol Chitosan/Dibenzaldehyde-Terminated Poly(ethylene glycol) Hydrogel with Inherent Antibacterial Properties. ACS applied bio materials. 6(2):552-565

Siregar, P., Audira, G., Castillo, A.L., Roldan, M.J.M., Suryanto, M.E., Liu, R.X., Lin, Y.T., Lai, Y.H., Hsiao, C.D. (2022) Comparison of the psychoactive activity of four primary Areca nut alkaloids in zebrafish by behavioral approach and molecular docking. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 155:113809

Farhan, A., Saputra, F., Suryanto, M.E., Humayun, F., Pajimna, R.M.B., Vasquez, R.D., Roldan, M.J.M., Audira, G., Lai, H.T., Lai, Y.H., Hsiao, C.D. (2022) OpenBloodFlow: A User-Friendly OpenCV-Based Software Package for Blood Flow Velocity and Blood Cell Count Measurement for Fish Embryos. Biology. 11(10):

Lin, H.C., Saputra, F., Audira, G., Lai, Y.H., Roldan, M.J.M., Alos, H.C., Aventurado, C.A., Vasquez, R.D., Tsai, G.J., Lim, K.H., Hsiao, C.D. (2022) Investigating Potential Cardiovascular Toxicity of Two Anti-Leukemia Drugs of Asciminib and Ponatinib in Zebrafish Embryos. International Journal of Molecular Sciences. 23(19):

Suryanto, M.E., Saputra, F., Kurnia, K.A., Vasquez, R.D., Roldan, M.J.M., Chen, K.H., Huang, J.C., Hsiao, C.D. (2022) Using DeepLabCut as a Real-Time and Markerless Tool for Cardiac Physiology Assessment in Zebrafish. Biology. 11(8)

Young, A.Y.W., Audira, G., Saputra, F., Alos, H.C., Aventurado, C.A., Lai, Y.H., Vasquez, R.D., Hsiao, C.D., Hung, C.H. (2022) Toxicity Assessment of an Anti-Cancer Drug of p-Toluene Sulfonamide in Zebrafish Larvae Based on Cardiovascular and Locomotion Activities. Biomolecules. 12(8)

Suryanto, M.E., Yang, C.C., Audira, G., Vasquez, R.D., Roldan, M.J.M., Ger, T.R., Hsiao, C.D. (2022) Evaluation of Locomotion Complexity in Zebrafish after Exposure to Twenty Antibiotics by Fractal Dimension and Entropy Analysis. Antibiotics (Basel, Switzerland). 11(8)

Audira, G., Suryanto, M.E., Chen, K.H., Vasquez, R.D., Roldan, M.J.M., Yang, C.C., Hsiao, C.D., Huang, J.C. (2022) Acute and Chronic Effects of Fin Amputation on Behavior Performance of Adult Zebrafish in 3D Locomotion Test Assessed with Fractal Dimension and Entropy Analyses and Their Relationship to Fin Regeneration. Biology. 11(7)

Lin, Y.T., Liu, R.X., Audira, G., Suryanto, M.E., Roldan, M.J.M., Lee, J.S., Ger, T.R., Hsiao, C.D. (2022) Lanthanides Toxicity in Zebrafish Embryos Are Correlated to Their Atomic Number. Toxics. 10(6)

Chan, K.Y., Yan, C.S., Roan, H.Y., Hsu, S.C., Tseng, T.L., Hsiao, C.D., Hsu, C.P., Chen, C.H. (2022) Skin cells undergo asynthetic fission to expand body surfaces in zebrafish. Nature. 605(7908):119-125

Farhan, A., Kurnia, K.A., Saputra, F., Chen, K.H., Huang, J.C., Roldan, M.J.M., Lai, Y.H., Hsiao, C.D. (2021) An OpenCV-Based Approach for Automated Cardiac Rhythm Measurement in Zebrafish from Video Datasets. Biomolecules. 11(10):

Duan, X.Y., Ma, R.J., Hsiao, C.D., Jiang, Z.Z., Zhang, L.Y., Zhang, Y., Liu, K.C. (2021) Tripterygium wilfordii multiglycoside-induced hepatotoxicity via inflammation and apoptosis in zebrafish. Chinese Journal of Natural Medicines. 19:750-757

Abbas, K., Saputra, F., Suryanto, M.E., Lai, Y.H., Huang, J.C., Yu, W.H., Chen, K.H., Lin, Y.T., Hsiao, C.D. (2021) Evaluation of Effects of Ractopamine on Cardiovascular, Respiratory, and Locomotory Physiology in Animal Model Zebrafish Larvae. Cells. 10(9):

Feng, Z., Lin, C., Tu, L., Su, M., Song, C., Liu, S., Suryanto, M.E., Hsiao, C.D., Li, L. (2021) FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish. Cells. 10(8):

Du, Z.C., Xia, Z.S., Zhang, M.Z., Wei, Y.T., Malhotra, N., Saputra, F., Audira, G., Roldan, M.J.M., Hsiao, C.D., Hao, E.W., Hou, X.T., Deng, J.G. (2021) Sub-lethal Camphor Exposure Triggers Oxidative Stress, Cardiotoxicity, and Cardiac Physiology Alterations in Zebrafish Embryos. Cardiovascular Toxicology. 21(11):901-913

Kurnia, K.A., Santoso, F., Sampurna, B.P., Audira, G., Huang, J.C., Chen, K.H., Hsiao, C.D. (2021) TCMacro: A Simple and Robust ImageJ-Based Method for Automated Measurement of Tail Coiling Activity in Zebrafish. Biomolecules. 11(8):

Li, P., Zhang, M., Xie, D., Zhang, X., Zhang, S., Gao, F., Wang, Y., Hsiao, C.D., Li, X., Liu, K. (2021) Characterization and bioactivities of phospholipids from squid viscera and gonads using ultra-performance liquid chromatography-Q-exactive orbitrap/mass spectrometry-based lipidomics and zebrafish models. Food & function. 12(17):7986-7996

Audira, G., Siregar, P., Chen, K.H., Roldan, M.J.M., Huang, J.C., Lai, H.T., Hsiao, C.D. (2021) Interspecies Behavioral Variability of Medaka Fish Assessed by Comparative Phenomics. International Journal of Molecular Sciences. 22(11):

Siregar, P., Audira, G., Feng, L.Y., Lee, J.H., Santoso, F., Yu, W.H., Lai, Y.H., Li, J.H., Lin, Y.T., Chen, J.R., Hsiao, C.D. (2021) Pharmaceutical Assessment Suggests Locomotion Hyperactivity in Zebrafish Triggered by Arecoline Might Be Associated with Multiple Muscarinic Acetylcholine Receptors Activation. toxins. 13(4):

Suryanto, M.E., Audira, G., Uapipatanakul, B., Hussain, A., Saputra, F., Siregar, P., Chen, K.H., Hsiao, C.D. (2021) Antidepressant Screening Demonstrated Non-Monotonic Responses to Amitriptyline, Amoxapine and Sertraline in Locomotor Activity Assay in Larval Zebrafish. Cells. 10(4):

Audira, G., Lee, J.S., Siregar, P., Malhotra, N., Rolden, M.J.M., Huang, J.C., Chen, K.H., Hsu, H.S., Hsu, Y., Ger, T.R., Hsiao, C.D. (2021) Comparison of the chronic toxicities of graphene and graphene oxide toward adult zebrafish by using biochemical and phenomic approaches. Environmental pollution (Barking, Essex : 1987). 278:116907

Gao, M., Xing, C., Jiang, X., Xu, L., Li, P., Hsiao, C.D. (2021) Highly selective fluorescence detection of Cu²⁺ based on Schiff base functionalized Periodic Mesoiporous Organosilicas. Luminescence : the journal of biological and chemical luminescence. 36(4):951-957

Zhang, F., Han, L., Wang, J., Shu, M., Liu, K., Zhang, Y., Hsiao, C., Tian, Q., He, Q. (2021) Clozapine Induced Developmental and Cardiac Toxicity on Zebrafish Embryos by Elevating Oxidative Stress. Cardiovascular Toxicology. 21(5):399-409

Wang, J., Liu, K., Mo, C., Oleksandr, M.H., Zhang, Y., Chen, J.R., Hsiao, C.D., Zhu, Q., He, Q. (2020) Nano-titanium nitride causes developmental toxicity in zebrafish through oxidative stress. Drug and chemical toxicology. 45(4):1660-1669

Lai, Y.H., Audira, G., Liang, S.T., Siregar, P., Suryanto, M.E., Lin, H.C., Villalobos, O., Villaflores, O.B., Hao, E., Lim, K.H., Hsiao, C.D. (2020) Duplicated dnmt3aa and dnmt3ab DNA Methyltransferase Genes Play Essential and Non-Overlapped Functions on Modulating Behavioral Control in Zebrafish. Genes. 11(11):

Robea, M.A., Jijie, R., Nicoara, M., Plavan, G., Ciobica, A.S., Solcan, C., Audira, G., Hsiao, C.D., Strungaru, S.A. (2020) Vitamin C Attenuates Oxidative Stress and Behavioral Abnormalities Triggered by Fipronil and Pyriproxyfen Insecticide Chronic Exposure on Zebrafish Juvenile. Antioxidants (Basel, Switzerland). 9(10):

Audira, G., Ngoc Anh, N.T., Ngoc Hieu, B.T., Malhotra, N., Siregar, P., Villalobos, O., Villaflores, O.B., Ger, T.R., Huang, J.C., Chen, K.H., Hsiao, C.D. (2020) Evaluation of the Adverse Effects of Chronic Exposure to Donepezil (An Acetylcholinesterase Inhibitor) in Adult Zebrafish by Behavioral and Biochemical Assessments. Biomolecules. 10(9):

Santoso, F., Farhan, A., Castillo, A.L., Malhotra, N., Saputra, F., Kurnia, K.A., Chen, K.H., Huang, J.C., Chen, J.R., Hsiao, C.D. (2020) An Overview of Methods for Cardiac Rhythm Detection in Zebrafish. Biomedicines. 8(9):

Hussain, A., Audira, G., Malhotra, N., Uapipatanakul, B., Chen, J.R., Lai, Y.H., Huang, J.C., Chen, K.H., Lai, H.T., Hsiao, C.D. (2020) Multiple Screening of Pesticides Toxicity in Zebrafish and Daphnia Based on Locomotor Activity Alterations. Biomolecules. 10(9):

Hsiao, C.D., Wu, H.H., Malhotra, N., Liu, Y.C., Wu, Y.H., Lin, Y.N., Saputra, F., Santoso, F., Chen, K.H. (2020) Expression and Purification of Recombinant GHK Tripeptides Are Able to Protect against Acute Cardiotoxicity from Exposure to Waterborne-Copper in Zebrafish. Biomolecules. 10(9):

Malhotra, N., Villaflores, O.B., Audira, G., Siregar, P., Lee, J.S., Ger, T.R., Hsiao, C.D. (2020) Toxicity Studies on Graphene-Based Nanomaterials in Aquatic Organisms: Current Understanding. Molecules. 25(16)

Siregar, P., Juniardi, S., Audira, G., Lai, Y.H., Huang, J.C., Chen, K.H., Chen, J.R., Hsiao, C.D. (2020) Method Standardization for Conducting Innate Color Preference Studies in Different Zebrafish Strains. Biomedicines. 8(8):

Audira, G., Siregar, P., Strungaru, S.A., Huang, J.C., Hsiao, C.D. (2020) Which Zebrafish Strains Are More Suitable to Perform Behavioral Studies? A Comprehensive Comparison by Phenomic Approach. Biology. 9(8)

Audira, G., Siregar, P., Chen, J.R., Lai, Y.H., Huang, J.C., Hsiao, C.D. (2020) Systematical exploration of the common solvent toxicity at whole organism level by behavioral phenomics in adult zebrafish. Environmental pollution (Barking, Essex : 1987). 266:115239

Malhotra, N., Lee, J.S., Liman, R.A.D., Ruallo, J.M.S., Villaflores, O.B., Ger, T.R., Hsiao. C.D. (2020) Potential Toxicity of Iron Oxide Magnetic Nanoparticles: A Review. Molecules. 25(14)

Chen, R.Y., Hieu, B.T.N., Audira, G., Lou, B., Lin, M.D., Hsiao, C.D. (2020) Meta-Transcriptomic Analysis of RNAseq Data Reveals Pacu and Loach Fish with Unusually High Levels of Myoglobin Expression in Skeletal Muscles. Animals : an open access journal from MDPI. 10(7)

Hussain, A., Audira, G., Siregar, P., Lin, Y.C., Villalobos, O., Villaflores, O., Wang, W.D., Hsiao, C.D. (2020) Waterborne Exposure of Paclobutrazol at Environmental Relevant Concentration Induce Locomotion Hyperactivity in Larvae and Anxiolytic Exploratory Behavior in Adult Zebrafish. International Journal of Environmental Research and Public Health. 17(13):

Chen, R.Y., Lin, C.J., Liang, S.T., Villalobos, O., Villaflores, O.B., Lou, B., Lai, Y.H., Hsiao, C.D. (2020) UVB Irradiation Induced Cell Damage and Early Onset of Junbb Expression in Zebrafish. Animals : an open access journal from MDPI. 10(6):

Balitaan, J.N.I., Hsiao, C.D., Yeh, J.M., Santiago, K.S. (2020) Innovation inspired by nature: Biocompatible self-healing injectable hydrogels based on modified-β-chitin for wound healing. International journal of biological macromolecules. 162:723-736

Malhotra, N., Audira, G., Chen, J.R., Siregar, P., Hsu, H.S., Lee, J.S., Ger, T.R., Hsiao, C.D. (2020) Surface Modification of Magnetic Nanoparticles by Carbon-Coating Can Increase Its Biosafety: Evidences from Biochemical and Neurobehavioral Tests in Zebrafish. Molecules. 25(9):

Lin, Y.N., Audira, G., Malhotra, N., Ngoc Anh, N.T., Siregar, P., Lu, J.H., Lee, H., Hsiao, C.D. (2020) A Novel Function of the Lysophosphatidic Acid Receptor 3 (LPAR3) Gene in Zebrafish on Modulating Anxiety, Circadian Rhythm Locomotor Activity, and Short-Term Memory. International Journal of Molecular Sciences. 21(8):

Bui Thi, N.H., Nguyen Thi, N.A., Audira, G., Siregar, P., Liang, S.T., Huang, J.C., Hsiao, C.D. (2020) Chronic Exposure to Low Concentration Lead Chloride-Induced Anxiety and Loss of Aggression and Memory in Zebrafish. International Journal of Molecular Sciences. 21(5):

Ngoc Hieu, B.T., Ngoc Anh, N.T., Audira, G., Juniardi, S., Liman, R.A.D., Villaflores, O.B., Lai, Y.H., Chen, J.R., Liang, S.T., Huang, J.C., Hsiao, C.D. (2020) Development of a Modified Three-Day T-maze Protocol for Evaluating Learning and Memory Capacity of Adult Zebrafish. International Journal of Molecular Sciences. 21(4):

Sarasamma, S., Audira, G., Siregar, P., Malhotra, N., Lai, Y.H., Liang, S.T., Chen, J.R., Chen, K.H., Hsiao, C.D. (2020) Nanoplastics Cause Neurobehavioral Impairments, Reproductive and Oxidative Damages, and Biomarker Responses in Zebrafish: Throwing up Alarms of Wide Spread Health Risk of Exposure. International Journal of Molecular Sciences. 21(4):

Li, X., Li, C., Zhu, Y., Shi, Y., Zhang, X., Zhang, S., Wang, L., Lin, H.W., Hou, H., Hsiao, C.D., Han, L., Liu, K. (2020) Lipids Fingerprinting of Different Materials Sources by UPLC-Q-Exactive Orbitrap/MS Approach and Their Zebrafish-based Activities Comparison. Journal of Agricultural and Food Chemistry. 68(7):2007-2015

Song, Z., Zhang, Y., Zhang, H., Rajendran, R.S., Wang, R., Hsiao, C.D., Li, J., Xia, Q., Liu, K. (2019) Isoliquiritigenin triggers developmental toxicity and oxidative stress-mediated apoptosis in zebrafish embryos/larvae via Nrf2-HO1/JNK-ERK/mitochondrion pathway. Chemosphere. 246:125727

Sarasamma, S., Audira, G., Samikannu, P., Juniardi, S., Siregar, P., Hao, E., Chen, J.R., Hsiao, C.D. (2019) Behavioral Impairments and Oxidative Stress in the Brain, Muscle, and Gill Caused by Chronic Exposure of C₇₀ Nanoparticles on Adult Zebrafish. International Journal of Molecular Sciences. 20(22):

Liang, S.T., Chen, J.R., Tsai, J.J., Lai, Y.H., Hsiao, C.D. (2019) Overexpression of Notch Signaling Induces Hyperosteogeny in Zebrafish. International Journal of Molecular Sciences. 20(15)

Huo, J., Yu, Q., Zhang, Y., Liu, K., Hsiao, C.D., Jiang, Z., Zhang, L. (2019) Triptolide-induced hepatotoxicity via apoptosis and autophagy in zebrafish. Journal of applied toxicology : JAT. 39(11):1532-1540

Zhang, Y., Cen, J., Jia, Z., Hsiao, C.D., Xia, Q., Wang, X., Chen, X., Wang, R., Jiang, Z., Zhang, L., Liu, K. (2019) Correction for Zhang et al., "Hepatotoxicity Induced by Isoniazid-Lipopolysaccharide through Endoplasmic Reticulum Stress, Autophagy, and Apoptosis Pathways in Zebrafish". Antimicrobial Agents and Chemotherapy. 63(7)

Audira, G., Sampurna, B.P., Juniardi, S., Liang, S.T., Lai, Y.H., Han, L., Hsiao, C.D. (2019) Establishing simple image-based methods and cost-effective instrument for toxicity assessment on circadian rhythm dysregulation in fish. Biology Open. 8(6):

Sampurna, B.P., Santoso, F., Lee, J.H., Yu, W.H., Wu, C.C., Audira, G., Juniardi, S., Chen, J.R., Lin, Y.T., Hsiao, C.D. (2019) Cardiac Rhythm and Molecular Docking Studies of Ion Channel Ligands with Cardiotoxicity in Zebrafish. Cells. 8(6)

Malhotra, N., Chen, J.R., Sarasamma, S., Audira, G., Siregar, P., Liang, S.T., Lai, Y.H., Lin, G.M., Ger, T.R., Hsiao, C.D. (2019) Ecotoxicity Assessment of Fe₃O₄ Magnetic Nanoparticle Exposure in Adult Zebrafish at an Environmental Pertinent Concentration by Behavioral and Biochemical Testing. Nanomaterials (Basel, Switzerland). 9(6):

Liang, S.T., Audira, G., Juniardi, S., Chen, J.R., Lai, Y.H., Du, Z.C., Lin, D.S., Hsiao, C.D. (2019) Zebrafish Carrying pycr1 Gene Deficiency Display Aging and Multiple Behavioral Abnormalities. Cells. 8(5):

Jia, Z.L., Cen, J., Wang, J.B., Zhang, F., Xia, Q., Wang, X., Chen, X.Q., Wang, R.C., Hsiao, C.D., Liu, K.C., Zhang, Y. (2019) Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway. Chemosphere. 227:541-550

Zhang, Y., Cen, J., Jia, Z., Hsiao, C.D., Xia, Q., Wang, X., Chen, X., Wang, R., Jiang, Z., Zhang, L., Liu, K. (2019) Hepatotoxicity induced by Isoniazid/Lipopolysaccharide through ERS-, autophagy- and apoptosis pathway in zebrafish. Antimicrobial Agents and Chemotherapy. 63(5):

Audira, G., Sarasamma, S., Chen, J.R., Juniardi, S., Sampurna, B.P., Liang, S.T., Lai, Y.H., Lin, G.M., Hsieh, M.C., Hsiao, C.D. (2018) Zebrafish Mutants Carrying Leptin a (lepa) Gene Deficiency Display Obesity, Anxiety, Less Aggression and Fear, and Circadian Rhythm and Color Preference Dysregulation. International Journal of Molecular Sciences. 19(12):

Jin, M., Xiao, Z., Zhang, S., Men, X., Li, X., Zhang, B., Zhou, T., Hsiao, C.D., Liu, K. (2018) Possible involvement of Fas/FasL-dependent apoptotic pathway in α-bisabolol induced cardiotoxicity in zebrafish embryos. Chemosphere. 219:557-566

Sarasamma, S., Lai, Y.H., Liang, S.T., Liu, K., Hsiao, C.D. (2018) The Power of Fish Models to Elucidate Skin Cancer Pathogenesis and Impact the Discovery of New Therapeutic Opportunities. International Journal of Molecular Sciences. 19(12)

Sarasamma, S., Audira, G., Juniardi, S., Sampurna, B.P., Lai, Y.H., Hao, E., Chen, J.R., Hsiao, C.D. (2018) Evaluation of the Effects of Carbon 60 Nanoparticle Exposure to Adult Zebrafish: A Behavioral and Biochemical Approach to Elucidate the Mechanism of Toxicity. International Journal of Molecular Sciences. 19(12):

Sarasamma, S., Audira, G., Juniardi, S., Sampurna, B.P., Liang, S.T., Hao, E., Lai, Y.H., Hsiao, C.D. (2018) Zinc Chloride Exposure Inhibits Brain Acetylcholine Levels, Produces Neurotoxic Signatures, and Diminishes Memory and Motor Activities in Adult Zebrafish. International Journal of Molecular Sciences. 19(10)

Xiong, X.Y., Liu, Y., Shan, L.T., Xu, Y.Q., Liang, J., Lai, Y.H., Hsiao, C.D. (2018) Evaluation of collagen mixture on promoting skin wound healing in zebrafish caused by acetic acid administration. Biochemical and Biophysical Research Communications. 505(2):516-522

Hsieh, F.C., Lu, Y.F., Liau, I., Chen, C.C., Cheng, C.M., Hsiao, C.D., Hwang, S.L. (2018) Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells. Scientific Reports. 8:7856

Sampurna, B.P., Audira, G., Juniardi, S., Lai, Y.H., and Hsiao, C.D. (2018) A Simple ImageJ-Based Method to Measure Cardiac Rhythm in Zebrafish Embryos. Inventions. 3(2)

Audira, G., Sampurna, B.P., Juniardi, S., Liang, S.T., Lai, Y.H., and Hsiao, C.D. (2018) A Simple Setup to Perform 3D Locomotion Tracking in Zebrafish by Using a Single Camera. Inventions. 3(1)

Schepis, A., Barker, A., Srinivasan, Y., Balouch, E., Zheng, Y., Lam, I., Clay, H., Hsiao, C.D., Coughlin, S.R. (2018) Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia. The Journal of cell biology. 217(3):1097-1112

Chen, J.R., Lai, Y.H., Tsai, J.J., Hsiao, C.D. (2017) Live Fluorescent Staining Platform for Drug-Screening and Mechanism-Analysis in Zebrafish for Bone Mineralization. Molecules. 22(12)

Sarasamma, S., Varikkodan, M.M., Liang, S.T., Lin, Y.C., Wang, W.P., Hsiao, C.D. (2017) Zebrafish: A Premier Vertebrate Model for Biomedical Research in Indian Scenario. Zebrafish. 14(6):589-605

Zhang, Y., Han, L., He, Q., Chen, W., Sun, C., Wang, X., Chen, X., Wang, R., Hsiao, C.D., Liu, K. (2017) A rapid assessment for predicting drug-induced hepatotoxicity using zebrafish. Journal of Pharmacological and Toxicological Methods. 84:102-110

Zhang, Y., Liu, K., Hassan, H.M., Guo, H., Ding, P., Han, L., He, Q., Chen, W., Hsiao, C.D., Zhang, L., Jiang, Z. (2016) L-FABP-deficiency provoked oxidative stress, inflammation and apoptosis-mediated hepatotoxicity induced by pyrazinamide on zebrafish larvae. Antimicrobial Agents and Chemotherapy. 60(12):7347-7356

Sun, G., Liu, K., Wang, X., Liu, X., He, Q., Hsiao, C.D. (2015) Identification and Expression Analysis of Zebrafish (Danio rerio) E-Selectin during Embryonic Development. Molecules. 20:18539-18550

Chang, T.Y., Huang, T.S., Wang, H.W., Chang, S.J., Lo, H.H., Chiu, Y.L., Wang, Y.L., Hsiao, C.D., Tsai, C.H., Chan, C.H., You, R.I., Wu, C.H., Tsai, T.N., Cheng, S.M., Cheng, C.C. (2014) miRNome traits analysis on endothelial lineage cells discloses biomarker potential circulating microRNAs which affect progenitor activities. BMC Genomics. 15:802

Huang, S.Y., Feng, C.W., Hung, H.C., Chakraborty, C., Chen, C.H., Chen, W.F., Jean, Y.H., Wang, H.M., Sung, C.S., Sun, Y.M., Wu, C.Y., Liu, W., Hsiao, C.D., Wen, Z.H. (2014) A Novel Zebrafish Model to Provide Mechanistic Insights into the Inflammatory Events in Carrageenan-Induced Abdominal Edema. PLoS One. 9:e104414

Chen, C.H., Lin, D.S., Cheng, C.W., Lin, C.J., Lo, Y.K., Yen, C.C., Lee, A.Y., Hsiao, C.D. (2014) Cdc6 cooperates with c-Myc to promote genome instability and EMT in zebrafish. Oncotarget. 5(15):6300-11

Feng, C.W., Wen, Z.H., Huang, S.Y., Hung, H.C., Chen, C.H., Yang, S.N., Chen, N.F., Wang, H.M., Hsiao, C.D., Chen, W.F. (2014) Effects of 6-Hydroxydopamine Exposure on Motor Activity and Biochemical Expression in Zebrafish (Danio Rerio) Larvae. Zebrafish. 11(3):227-39

Chen, S.Y., Shih, H.Y., Lin, S.J., Hsiao, C.D., Li, Z.C., and Cheng, Y.C. (2013) Etv5a regulates the proliferation of ventral mesoderm cells and the formation of hemato-vascular derivatives. Journal of Cell Science. 126(Pt 24):5626-34

Shih, D.F., Hsiao, C.D., Min, M.Y., Lai, W.S., Yang, C.W., Lee, W.T., and Lee, S.J. (2013) Aromatic L-Amino Acid Decarboxylase (AADC) Is Crucial for Brain Development and Motor Functions. PLoS One. 8(8):e71741

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