FIGURE SUMMARY
Title

Zinc oxide-induced changes to sunscreen ingredient efficacy and toxicity under UV irradiation

Authors
Ginzburg, A.L., Blackburn, R.S., Santillan, C., Truong, L., Tanguay, R.L., Hutchison, J.E.
Source
Full text @ Photochem. Photobiol. Sci.
Chart 1

Structures of the UV-filters used in the small-molecule formulations and the type of UV light they absorb
Fig. 1

UV–Vis spectra showing photodegradation of mixtures 1–5 measured in 99:1 IPA/DMSO

Fig. 2

Summary of changes in toxicity to mixtures 1–5 following UV irradiation
Fig. 3

UV–Vis spectra of mixture 1 + ZnO particles before and after 2 h of UV irradiation
Fig. 4

Changes in zebrafish development over five days at ten different endpoints. Animals were exposed to 99:1 water/DMSO solutions containing 0.0014% (w/w) organic filters (mixture 1; panels a–c and 0.0005% (w/w) ZnO (panels a, b and d). Key to endpoints: mortality (MORT), excess fluid accumulation around yolk sac (YSE), abnormal eye placement or size (EYE), visibly malformed snout (SNOUT), jaw (JAW), excessive fluid accumulation around pericardial edema (PE), under developed or malformed pectoral fin (PFIN) or caudal fin (CFIN), body length shorter than normal (TRUNK), and body axis curvature (AXIS)
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Photochem. Photobiol. Sci.
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