FIGURE SUMMARY
Title

Clitorienolactones and Isoflavonoids of Clitorea ternatea Roots Alleviate Stress-Like Symptoms in a Reserpine-Induced Zebrafish Model

Authors
Ngadni, M.A., Akhtar, M.T., Ismail, I.S., Norazhar, A.I., Lee, S.Y., Maulidiani, M., Shaari, K.
Source
Full text @ Molecules
Figure 1

The LC–DAD (A) and LC–MS (B) base peak chromatogram profiles of Clitorea ternatea crude root extract in negative ion mode.

Figure 2

Proposed characteristic fragmentation pathway of compounds 17, 18, 23, and 24 (Clitorienolactones D, C, B, and A, respectively).

Figure 3

The LC–DAD and LC–MS base peak chromatogram profiles of the 50% MeOH (A,B) and EA (C,D) fractions of Clitorea ternatea roots, in negative ion mode.

Figure 4

Behavioral effects of the crude methanolic extract, EA, and 50% MeOH fractions of Clitorea ternatea roots on the reserpine-induced stress zebrafish model. Behavioral measurements were recorded at (A) 24 h after IP injection of reserpine, (B) 24 h after treatments, (C) 48 h after treatments, and (D) 72 h after treatments for each group, i.e., fluoxetine (0.6 mg/mL, 30 min), CTRE, EA, and 50% MeOH fractions groups (35 mg/mL, 6 h). All values are reported as mean percentage ± SE (n = 10 per group). Duncan’s post-hoc test was used for significant differences, where * = p < 0.05, ** = p < 0.01, and *** = p < 0.001. PBS: phosphate buffer saline; FX: fluoxetine; RES: reserpine; CTRE: crude C. ternatea extract; EA: ethyl acetate; MEOH: 50% methanol.
Figure 5

Groupings and experimental workflow of the zebrafish in vivo assay.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Molecules
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.