FIGURE SUMMARY
Title

Rho GTPases Signaling in Zebrafish Development and Disease

Authors
Boueid, M.J., Mikdache, A., Lesport, E., Degerny, C., Tawk, M.
Source
Full text @ Cells
Figure 1

Role of Elmo1/Rac1 signaling during zebrafish Schwann cell development. Elmo1 acts in association with Dock1 to enhance Rac-specific guanine nucleotide exchange factor (GEF) activity of Dock1 by mediating a GDP to GTP exchange on Rac1. Elmo1 function is linked to Rac1 activity within Schwann cells and contributes to the radial sorting process in which a Schwann cell associates with a single axonal segment via cytoskeletal rearrangements. SC, Schwann cell.
Figure 2

Schematic illustration of the main activities of Rac1, Cdc42 and RhoA in zebrafish and some of their regulators. NC, Neural Crest; SC, Schwann cell.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cells
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