ZFIN All Figures, Sridevi <i>et al.</i>, 2014

Sridevi et al., 2014

ZDB-PUB-160121-8
PMID:26786625
Fig. 1
Fig. 3
Fig. 6
Fig. 7

FIGURE SUMMARY

Title: Optimization and validation of Mycobacterium marinum-induced adult zebrafish model for evaluation of oral anti-tuberculosis drugs
Authors: Sridevi, J.P., Anantaraju, H.S., Kulkarni, P., Yogeeswari, P., Sriram, D.
Source: Full text @ Int J Mycobacteriol

Fig. 1

M. marinum-induced adult zebrafish with red lesions & squamous eruptions on dorsal and lateral sides observed during the study.

Fig. 3

Percentage body weight reduction observed in groups control-uninfected, I, II, III (Mean ± S.E.M., n = 10) on days 7 and 14 during the bacterial optimization study of M. marinum-induced adult zebrafish model. The statistical significance (^∗p < 0.05, ^∗∗p < 0.01 and ^∗∗∗p < 0.001) with respect to un-infected control group has been analyzed by one-way ANOVA using GraphPad Prism Software.

PHENOTYPE:

Fish:	WT
Condition:	bacterial treatment: Mycobacterium marinum
Observed In:	whole organism
Stage:	Adult

Phenotype details

Fig. 6

A. Mean body weight changes observed (Mean ± S.E.M., n = 10) with respective days post infection for all the groups during the study of M. marinum-induced adult zebrafish model.

B. Percentage body weight reduction (Mean ± S.E.M., n = 10) over the study period for control and treated groups of M. marinum-induced adult zebrafish model. The statistical significance (^∗p < 0.05, ^∗∗p < 0.01 and ^∗∗∗p < 0.001) with respect to un-infected control group has been analyzed by one-way ANOVA using GraphPad Prism Software.

PHENOTYPE:

Fish:	WT
Conditions:	bacterial treatment: Mycobacterium marinum, chemical treatment: ethambutol bacterial treatment: Mycobacterium marinum, chemical treatment: isoniazide bacterial treatment: Mycobacterium marinum, chemical treatment: moxifloxacin bacterial treatment: Mycobacterium marinum, chemical treatment: rifampicin
Observed In:	whole organism
Stage:	Adult

Phenotype details

Fig. 7

Flow chart demonstrating the standardization process followed in developing adult Zebrafish tuberculosis model for evaluation of oral anti-tuberculosis drugs.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int J Mycobacteriol

Sridevi et al., 2014 ZDB-PUB-160121-8 PMID:26786625

Optimization and validation of Mycobacterium marinum-induced adult zebrafish model for evaluation of oral anti-tuberculosis drugs

Sridevi et al., 2014

ZDB-PUB-160121-8
PMID:26786625