FIGURE SUMMARY
- Title
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Evolutionary constraint on Otx2 neuroectoderm enhancers-deep conservation from skate to mouse and unique divergence in teleost
- Authors
- Kurokawa, D., Sakurai, Y., Inoue, A., Nakayama, R., Takasaki, N., Suda, Y., Miyake, T., Amemiya, C.T., and Aizawa, S.
- Source
- Full text @ Proc. Natl. Acad. Sci. USA
Activity pattern of zebrafish FM enhancer during zebrafish anterior neuroectoderm development. EGFP mRNA expression driven by zfFM in a typical permanent transgenic zebrafish line (B, D, F, H, J, and L) is compared with endogenous Otx2 mRNA expression (A, C, E, G, I, and K). All images are lateral views. (I–L) are views of head region in (E–H) at high magnification. Arrows in F and H indicate ectopic expression in hindbrain. A solid arrowhead in K indicates the presence of the endogenous Otx2 expression and open arrowheads in J and L indicate the absence of the transgenic EGFP expression in tegmentum. |
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Full text @ Proc. Natl. Acad. Sci. USA