GRL-0617

Term ID

CHEBI:167176

Synonyms

5-amino-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]benzamide
5-amino-2-methyl-N-[(1R)-1-(naphthalen-1-yl)ethyl]benzamide
5-amino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide
GRL 0617
GRL0617

Definition

A benzamide resulting from the formal condensation of the carboxy group of 5-amino-2-methylbenzoic acid with the amino group of (1R)-1-(naphthalen-1-yl)ethan-1-amine. It is a potent noncovalent inhibitor (IC50 = 600 nM) of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzamides naphthalenes secondary carboxamide substituted aniline

benzamides naphthalenes secondary carboxamide substituted aniline Show first 5 Terms
has_role: anticoronaviral agent protease inhibitor

anticoronaviral agent protease inhibitor Show first 5 Terms
inverse has_functional_parent: KOM70144

KOM70144 Show first 5 Terms

Phenotype

Phenotype resulting from GRL-0617

Phenotype where environments contain GRL-0617

Phenotype modified by environments containing GRL-0617

Human Disease / Model Data

Citations