| ZFIN ID: ZDB-EXP-180220-5 |
Experiment Conditions Description: chemical ablation: dopaminergic neuron, chemical treatment by injection: oxidopamine, chemical treatment by environment: methionine
| chemical ablation: dopaminergic neuron |
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| Name: | chemical ablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses a chemical to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000169] |
| Name: | dopaminergic neuron |
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| Synonyms: | dopaminergic neurons |
| Definition: | A neuron that releases dopamine as a neurotransmitter. |
| Ontology: | Anatomy Ontology [ZFA:0009301] |
| chemical treatment by injection: oxidopamine |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | oxidopamine |
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| Synonyms: | 2,4,5-trihydroxyphenethylamine, 5-(2-aminoethyl)benzene-1,2,4-triol, 6-hydroxydopamine, 6-OHDA, hydroxydopamine, oxidopamina, oxidopamine, oxidopaminum, topamine |
| Definition: | A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease). |
| Ontology: | ChEBI [CHEBI:78741] ( EBI ) |
| chemical treatment by environment: methionine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | methionine |
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| Synonyms: | 2-amino-4-(methylsulfanyl)butanoic acid, 2-amino-4-(methylthio)butanoic acid, 2-Amino-4-(methylthio)butyric acid, alpha-amino-gamma-methylmercaptobutyric acid, DL-Methionine, Hmet, M, Met, Methionin, methionine, metionina, Racemethionine |
| Definition: | A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. |
| Ontology: | ChEBI [CHEBI:16811] ( EBI ) |
| Publication: | Li et al., 2017 |
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