ZFIN ID: ZDB-EXP-131002-7
Experiment Conditions Description: cancer xenotransplantation, chemical treatment: vatalanib
cancer xenotransplantation
Name: cancer xenotransplantation
Synonyms:
Definition: Xenotransplantation condition in which cancer cells are injected or grafted into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000236]
chemical treatment: vatalanib
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: vatalanib
Synonyms: CGP 79787, CGP-79787, CGP79787, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine, N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine, N-(p-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine, PTK 787, PTK-787, PTK/ZK, PTK787, vatalanib, ZK-232934
Definition: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit.
Ontology: ChEBI [CHEBI:90620]  ( EBI )
Publication: Hollenbach et al., 2013