vatalanib

Term ID

CHEBI:90620

Synonyms

CGP 79787
CGP-79787
CGP79787
N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
N-(p-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine
PTK 787
PTK-787
PTK/ZK
PTK787
vatalanib
ZK-232934

Definition

A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibitor for all isoforms of VEGFR, PDGFR and c-Kit.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: monochlorobenzenes phthalazines pyridines secondary amino compound

monochlorobenzenes phthalazines pyridines secondary amino compound Show first 5 Terms
has_role: angiogenesis inhibitor antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor vascular endothelial growth factor receptor antagonist

angiogenesis inhibitor antineoplastic agent EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor vascular endothelial growth factor receptor antagonist Show first 5 Terms
inverse has_part: vatalanib succinate

vatalanib succinate Show first 5 Terms

Phenotype

Phenotype resulting from vatalanib

Phenotype where environments contain vatalanib

Phenotype modified by environments containing vatalanib

Human Disease / Model Data

Citations