| ZFIN ID: ZDB-EXP-160331-7 |
Experiment Conditions Description: bacterial treatment: Mycobacterium marinum, chemical treatment: ethambutol
| bacterial treatment: Mycobacterium marinum |
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| Name: | bacterial treatment |
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| Synonyms: | |
| Definition: | Biological treatment in which fish have been infected with bacteria. This infection can be done by addition of bacteria in the water or by injection of bacteria, (for example in the brain ventricle, in the caudal vein, in the yolk sac), or ingestion, or other means. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000106] |
| Name: | Mycobacterium marinum |
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| Synonyms: | Mycobacterium balnei, Mycobacterium platypoecilus |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:1781] |
| chemical treatment: ethambutol |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | ethambutol |
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| Synonyms: | (+)-2,2'-(ethylenediimino)di-1-butanol, (+)-ethambutol, (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine, (+)-S,S-ethambutol, (2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol, (2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol, (S,S)-ethambutol, EMB, etambutol, ethambutol, ethambutolum, S,S-Ethambutol |
| Definition: | An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. |
| Ontology: | ChEBI [CHEBI:4877] ( EBI ) |
| Publication: | Sridevi et al., 2014 |
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