Search Ontology:
ChEBI
ethambutol
- Term ID
- CHEBI:4877
- Synonyms
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- (+)-2,2'-(ethylenediimino)di-1-butanol
- (+)-ethambutol
- (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamine
- (+)-S,S-ethambutol
- (2S,2'S)-2,2'-(ethane-1,2-diyldiimino)dibutan-1-ol
- (2S,7S)-2,7-diethyl-3,6-diazaoctane-1,8-diol
- (S,S)-ethambutol
- EMB
- etambutol
- ethambutol
- ethambutolum
- S,S-Ethambutol
- Definition
- An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone.
- References
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- Beilstein:6312870
- CAS:74-55-5
- DrugBank:DB00330
- Drug_Central:1073
- KEGG:C06984
- KEGG:D07925
- PMID:10649975
- PMID:10891117
- PMID:10966749
- PMID:12182855
- PMID:14695841
- PMID:14698152
- PMID:15225698
- PMID:16005211
- PMID:16759086
- PMID:16870429
- PMID:17210775
- PMID:17239593
- PMID:17276683
- PMID:17315960
- PMID:17331717
- PMID:17562368
- PMID:17851083
- PMID:17888665
- PMID:19524332
- PMID:19648006
- PMID:3934384
- Reaxys:6312870
- Wikipedia:Ethambutol
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
-
- has_role
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- inverse has_part
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Show first 5 Terms
Phenotype
Phenotype resulting from ethambutol
Phenotype where environments contain ethambutol
Phenotype modified by environments containing ethambutol
Human Disease / Model Data
Citations