TALEN

TALEN3-pitx2

ID
ZDB-TALEN-180731-1
Name
TALEN3-pitx2
Previous Names
None
Target
Target Sequence 1
5' - TTTCAGAGGAATCGCTATC - 3'
ZFIN BLAST NCBI BLAST Ensembl
Target Sequence 2
5' - GTCCAAACGGCGATCTCCT - 3'
ZFIN BLAST NCBI BLAST Ensembl
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
mw709 pitx2
Expression
Gene expression in Wild Types + TALEN3-pitx2
No data available
Phenotype
Phenotype resulting from TALEN3-pitx2
No data available
Phenotype of all Fish created by or utilizing TALEN3-pitx2
Phenotype Fish Conditions Figures
eye col1a2 expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
Meckel's cartilage size, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
iris ventral region morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
eye tert expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
eye wnt7aa expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
corneal stroma decreased thickness, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
ceratohyal cartilage position, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
corneal stroma Ab3-col1a1a labeling spatial pattern, abnormal pitx2mw709/mw709 standard conditions Fig. 7 with image from Hendee et al., 2018
iris absent, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
anterior chamber eye morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image,  Fig. 5 with image from Hendee et al., 2018
iris hypoplastic, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
annular ligament morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 5 with image from Hendee et al., 2018
eye cartilage tissue Ab3-col1a1a labeling mislocalised, abnormal pitx2mw709/mw709 standard conditions Fig. 7 with image from Hendee et al., 2018
corneal stroma increased thickness, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image from Hendee et al., 2018
eye wnt4 expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
eye col5a2b expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
corneal endothelium morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image,  Fig. 6 with image from Hendee et al., 2018
corneal stroma undulate, abnormal pitx2mw709/mw709 standard conditions Fig. 5 with image,  Fig. 6 with image from Hendee et al., 2018
cornea abutting lens capsule, abnormal pitx2mw709/mw709 standard conditions Fig. 5 with image from Hendee et al., 2018
optic fissure closure incomplete, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
eye decreased size, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image,  Fig. 6 with image from Hendee et al., 2018
palatoquadrate cartilage malformed, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
corneal endothelium Ab9-cdh2 labeling absent, abnormal pitx2mw709/mw709 standard conditions Fig. 7 with image from Hendee et al., 2018
corneal endothelium disorganized, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
corneal epithelium Ab1-keratan sulfate labeling mislocalised, abnormal pitx2mw709/mw709 standard conditions Fig. 7 with image from Hendee et al., 2018
corneal stroma position, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image from Hendee et al., 2018
eye morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image,  Fig. 4 with image,  Fig. 6 with image from Hendee et al., 2018
lens elongated, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
ceratohyal cartilage size, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
iris decreased size, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
Meckel's cartilage malformed, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
corneal endothelium increased thickness, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
corneal epithelium morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
corneal epithelium Ab9-cdh2 labeling decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 7 with image from Hendee et al., 2018
anterior chamber eye absent, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
corneal epithelium irregular thickness, abnormal pitx2mw709/mw709 standard conditions Fig. 5 with image from Hendee et al., 2018
ethmoid cartilage morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
corneal epithelium vacuolated, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image from Hendee et al., 2018
eye dkk2 expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
eye col1a1a expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
ventral mandibular arch morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
corneal epithelium undulate, abnormal pitx2mw709/mw709 standard conditions Fig. 5 with image from Hendee et al., 2018
anterior chamber eye decreased size, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image,  Fig. 5 with image from Hendee et al., 2018
ethmoid cartilage size, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
lens capsule morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image from Hendee et al., 2018
iris stroma morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image,  Fig. 5 with image from Hendee et al., 2018
corneal stroma disorganized, abnormal pitx2mw709/mw709 standard conditions Fig. 7 with image from Hendee et al., 2018
eye wnt3 expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
anterior segment eye integument mislocalised, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
eye wnt6b expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
eye opacity, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
ceratohyal cartilage malformed, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
eye disorganized, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
corneal stroma irregular thickness, abnormal pitx2mw709/mw709 standard conditions Fig. 5 with image from Hendee et al., 2018
corneal stroma morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image,  Fig. 5 with image,  Fig. 6 with image,  Fig. 7 with image from Hendee et al., 2018
palatoquadrate cartilage size, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
corneal stroma Ab1-keratan sulfate labeling spatial pattern, abnormal pitx2mw709/mw709 standard conditions Fig. 7 with image from Hendee et al., 2018
anterior segment eye cartilage tissue mislocalised, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
eye wnt10a expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
cornea morphology, abnormal pitx2mw709/mw709 standard conditions Fig. 4 with image from Hendee et al., 2018
corneal epithelium increased thickness, abnormal pitx2mw709/mw709 standard conditions Fig. 6 with image from Hendee et al., 2018
eye col5a3b expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
eye absent, abnormal pitx2mw709/mw709 standard conditions Fig. 3 with image from Hendee et al., 2018
eye wnt9b expression decreased amount, abnormal pitx2mw709/mw709 standard conditions Fig. 8 from Hendee et al., 2018
Citations
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