PUBLICATION
            Zebrafish genomics: from mutants to genes
- Authors
- Postlethwait, J.H. and Talbot, W.S.
- ID
- ZDB-PUB-970602-15
- Date
- 1997
- Source
- Trends in genetics : TIG 13(5): 183-190 (Review)
- Registered Authors
- Postlethwait, John H., Talbot, William S.
- Keywords
- none
- MeSH Terms
- 
    
        
        
            
                - Chromosome Mapping*
- Animals
- Mutation*
- Zebrafish/genetics*
- Cloning, Molecular/methods
 
- PubMed
- 9154001 Full text @ Trends Genet.
            Citation
        
        
            Postlethwait, J.H. and Talbot, W.S. (1997) Zebrafish genomics: from mutants to genes. Trends in genetics : TIG. 13(5):183-190.
        
    
                
                    
                        Abstract
                    
                    
                
                
            
        
        
    
        
            
            
 
    
    
        
    
    
    
        
                Exquisite embryonic lethal mutations have been isolated in hundreds of genes necessary for zebrafish development. Analysis of this resource promises to enhance our understanding of the molecular genetic mechanisms of vertebrate development. This review discusses the state of the zebrafish genome project and the genetic trickery that can expedite molecular isolation of genes disrupted by these mutations.
            
    
        
        
    
    
    
                
                    
                        Genes / Markers
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Expression
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Phenotype
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Mutations / Transgenics
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Human Disease / Model
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Sequence Targeting Reagents
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Fish
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Orthology
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Engineered Foreign Genes
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    
                
                    
                        Mapping
                    
                    
                
                
            
        
        
    
        
            
            
        
        
    
    
    