PUBLICATION
Expression of taste sentinels, T1R, T2R, and PLCß2, on the passageway for olfactory signals in zebrafish
- Authors
- Birdal, G., D'Gama, P.P., Jurisch-Yaksi, N., Korsching, S.I.
- ID
- ZDB-PUB-231017-60
- Date
- 2023
- Source
- Chemical senses 48: (Journal)
- Registered Authors
- Jurisch-Yaksi, Nathalie, Korsching, Sigrun
- Keywords
- T1R, T2R, nostril, olfaction, taste, zebrafish
- MeSH Terms
-
- Animals
- Phospholipase C beta/metabolism
- Smell/physiology
- Taste/physiology
- Taste Buds*/metabolism
- Zebrafish*/metabolism
- PubMed
- 37843175 Full text @ Chem. Senses
Citation
Birdal, G., D'Gama, P.P., Jurisch-Yaksi, N., Korsching, S.I. (2023) Expression of taste sentinels, T1R, T2R, and PLCß2, on the passageway for olfactory signals in zebrafish. Chemical senses. 48:.
Abstract
The senses of taste and smell detect overlapping sets of chemical compounds in fish, e.g. amino acids are detected by both senses. However, so far taste and smell organs appeared morphologically to be very distinct, with a specialized olfactory epithelium for detection of odors and taste buds located in the oral cavity and lip for detection of tastants. Here we report dense clusters of cells expressing T1R and T2R receptors as well as their signal transduction molecule PLCß2 in nostrils of zebrafish, i.e. on the entrance funnel through which odor molecules must pass to be detected by olfactory sensory neurons. Quantitative evaluation shows the density of these chemosensory cells in the nostrils to be as high or higher than that in the established taste organs oral cavity and lower lip. Hydrodynamic flow is maximal at the nostril rim enabling high throughput chemosensation in this organ. Taken together, our results suggest a sentinel function for these chemosensory cells in the nostril.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping