PUBLICATION
Comparison of anxiety-like and social behaviour in medaka and zebrafish
- Authors
- Lucon-Xiccato, T., Loosli, F., Conti, F., Foulkes, N.S., Bertolucci, C.
- ID
- ZDB-PUB-220630-1
- Date
- 2022
- Source
- Scientific Reports 12: 10926 (Journal)
- Registered Authors
- Bertolucci, Cristiano, Foulkes, Nicholas-Simon, Loosli, Felix, Lucon-Xiccato, Tyrone
- Keywords
- none
- MeSH Terms
-
- Animals
- Anxiety
- Anxiety Disorders
- Oryzias*
- Social Behavior
- Zebrafish
- PubMed
- 35764691 Full text @ Sci. Rep.
Citation
Lucon-Xiccato, T., Loosli, F., Conti, F., Foulkes, N.S., Bertolucci, C. (2022) Comparison of anxiety-like and social behaviour in medaka and zebrafish. Scientific Reports. 12:10926.
Abstract
The medaka, Oryzias latipes, is rapidly growing in importance as a model in behavioural research. However, our knowledge of its behaviour is still incomplete. In this study, we analysed the performance of medaka in 3 tests for anxiety-like behaviour (open-field test, scototaxis test, and diving test) and in 3 sociability tests (shoaling test with live stimuli, octagonal mirror test, and a modified shoaling test with mirror stimulus). The behavioural response of medaka was qualitatively similar to that observed in other teleosts in the open-field test (thigmotaxis), and in 2 sociability tests, the shoaling test and in the octagonal mirror test (attraction towards the social stimulus). In the remaining tests, medaka did not show typical anxiety (i.e., avoidance of light environments and preference for swimming at the bottom of the aquarium) and social responses (attraction towards the social stimulus). As a reference, we compared the behaviour of the medaka to that of a teleost species with well-studied behaviour, the zebrafish, tested under the same conditions. This interspecies comparison indicates several quantitative and qualitative differences across all tests, providing further evidence that the medaka responds differently to the experimental settings compared to other fish models.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping