ZFIN ID: ZDB-PERS-001110-8
Foulkes, Nicholas-Simon
Email: nicholas.foulkes@kit.edu
URL: http://www.itg.kit.edu/foulkes.php
Affiliation: Foulkes Lab
Address: Karlsruhe Institute of Technology (KIT) Campus North Institute of Toxicology and Genetics (ITG) Hermann-von-Helmholtz-Platz 1 76344 Eggenstein-Leopoldshafen Germany
Country: Germany
Phone: +49 721 608-23394
Fax: +49 721 608-23354
ORCID ID:


BIOGRAPHY AND RESEARCH INTERESTS


PUBLICATIONS
Schalm, G., Bruns, K., Drachenberg, N., Geyer, N., Foulkes, N.S., Bertolucci, C., Gerlach, G. (2021) Finding Nemo's clock reveals switch from nocturnal to diurnal activity. Scientific Reports. 11:6801
Zhao, H., Li, H., Du, J., Di Mauro, G., Lungu-Mitea, S., Geyer, N., Vallone, D., Bertolucci, C., Foulkes, N.S. (2021) Regulation of ddb2 expression in blind cavefish and zebrafish reveals plasticity in the control of sunlight-induced DNA damage repair. PLoS Genetics. 17:e1009356
Guarino, A.M., Mauro, G.D., Ruggiero, G., Geyer, N., Delicato, A., Foulkes, N.S., Vallone, D., Calabrò, V. (2019) YB-1 recruitment to stress granules in zebrafish cells reveals a differential adaptive response to stress. Scientific Reports. 9:9059
Pylatiuk, C., Zhao, H., Gursky, E., Reischl, M., Peravali, R., Foulkes, N., Loosli, F. (2019) DIY Automated Feeding and Motion Recording System for the Analysis of Fish Behavior. SLAS technology. 24(4):394-398
Zhao, H., Di Mauro, G., Lungu-Mitea, S., Negrini, P., Guarino, A.M., Frigato, E., Braunbeck, T., Ma, H., Lamparter, T., Vallone, D., Bertolucci, C., Foulkes, N.S. (2018) Modulation of DNA Repair Systems in Blind Cavefish during Evolution in Constant Darkness. Current biology : CB. 28(20):3229-3243.e4
Pagano, C., Siauciunaite, R., Idda, M.L., Ruggiero, G., Ceinos, R.M., Pagano, M., Frigato, E., Bertolucci, C., Foulkes, N.S., Vallone, D. (2018) Evolution shapes the responsiveness of the D-box enhancer element to light and reactive oxygen species in vertebrates. Scientific Reports. 8:13180
Sloin, H.E., Ruggiero, G., Rubinstein, A., Smadja Storz, S., Foulkes, N.S., Gothilf, Y. (2018) Interactions between the circadian clock and TGF-β signaling pathway in zebrafish. PLoS One. 13:e0199777
Ceinos, R.M., Frigato, E., Pagano, C., Fröhlich, N., Negrini, P., Cavallari, N., Vallone, D., Fuselli, S., Bertolucci, C., Foulkes, N.S. (2018) Mutations in blind cavefish target the light-regulated circadian clock gene, period 2. Scientific Reports. 8:8754
Dekens, M.P., Foulkes, N.S., Tessmar-Raible, K. (2017) Instrument design and protocol for the study of light controlled processes in aquatic organisms, and its application to examine the effect of infrared light on zebrafish. PLoS One. 12:e0172038
Pagano, C., di Martino, O., Ruggiero, G., Guarino, A.M., Mueller, N., Siauciunaite, R., Reischl, M., Foulkes, N.S., Vallone, D., Calabrò, V. (2017) The tumor-associated YB-1 protein: new player in the circadian control of cell proliferation. Oncotarget. 8(4):6193-6205
Ben-Moshe Livne, Z., Alon, S., Vallone, D., Bayleyen, Y., Tovin, A., Shainer, I., Nisembaum, L.G., Aviram, I., Smadja-Storz, S., Fuentes, M., Falcón, J., Eisenberg, E., Klein, D.C., Burgess, H.A., Foulkes, N.S., Gothilf, Y. (2016) Genetically Blocking the Zebrafish Pineal Clock Affects Circadian Behavior. PLoS Genetics. 12:e1006445
Ben-Moshe, Z., Alon, S., Mracek, P., Faigenbloom, L., Tovin, A., Vatine, G.D., Eisenberg, E., Foulkes, N.S., and Gothilf, Y. (2014) The light-induced transcriptome of the zebrafish pineal gland reveals complex regulation of the circadian clockwork by light. Nucleic acids research. 42(6):3750-67
Villamizar, N., Vera, L.M., Foulkes, N.S., and Sánchez-Vázquez, F.J. (2014) Effect of Lighting Conditions on Zebrafish Growth and Development. Zebrafish. 11(2):173-81
Lahiri, K., Froehlich, N., Heyd, A., Foulkes, N.S., Vallone, D. (2014) Developmental stage-specific regulation of the circadian clock by temperature in zebrafish. BioMed Research International. 2014:930308
Ben-Moshe, Z., Foulkes, N.S., Gothilf, Y. (2014) Functional Development of the Circadian Clock in the Zebrafish Pineal Gland. BioMed Research International. 2014:235781
Mracek, P., Pagano, C., Fröhlich, N., Idda, M.L., Cuesta, I.H., Lopez-Olmeda, J.F., Sánchez-Vázquez, F.J., Vallone, D., and Foulkes, N.S. (2013) ERK Signaling Regulates Light-Induced Gene Expression via D-Box Enhancers in a Differential, Wavelength-Dependent Manner. PLoS One. 8(6):e67858
Cavodeassi, F., Bene, F.D., Fürthauer, M., Grabher, C., Herzog, W., Lehtonen, S., Linker, C., Mercader, N., Mikut, R., Norton, W., Strähle, U., Tiso, N., and Foulkes, N.S. (2013) Report of the Second European Zebrafish Principal Investigator Meeting in Karlsruhe, Germany, March 21-24, 2012. Zebrafish. 10(1):119-23
Elbaz, I., Foulkes, N.S., Gothilf, Y., and Appelbaum, L. (2013) Circadian clocks, rhythmic synaptic plasticity and the sleep-wake cycle in zebrafish. Frontiers in neural circuits. 7:9
Smadja Storz, S., Tovin, A., Mracek, P., Alon, S., Foulkes, N.S., and Gothilf, Y. (2013) Casein kinase 1delta activity: a key element in the zebrafish circadian timing system. PLoS One. 8(1):e54189
Idda, M.L., Bertolucci, C., Vallone, D., Gothilf, Y., Sánchez-Vázquez, F.J., and Foulkes, N.S. (2012) Circadian clocks: Lessons from fish. Progress in brain research. 199:41-57
Idda, M.L., Kage, E., Lopez-Olmedam, J.F., Mracek, P., Foulkes, N.S., and Vallone, D. (2012) Circadian timing of injury-induced cell proliferation in zebrafish. PLoS One. 7(3):e34203
Mracek, P., Santoriello, C., Idda, M.L., Pagano, C., Ben-Moshe, Z., Gothilf, Y., Vallone, D., and Foulkes, N.S. (2012) Regulation of per and cry Genes Reveals a Central Role for the D-Box Enhancer in Light-Dependent Gene Expression. PLoS One. 7(12):e51278
Tovin, A., Alon, S., Ben-Moshe, Z., Mracek, P., Vatine, G., Foulkes, N.S., Jacob-Hirsch, J., Rechavi, G., Toyama, R., Coon, S.L., Klein, D.C., Eisenberg, E., and Gothilf, Y. (2012) Systematic Identification of Rhythmic Genes Reveals camk1gb as a New Element in the Circadian Clockwork. PLoS Genetics. 8(12):e1003116
Cavallari, N., Frigato, E., Vallone, D., Fröhlich, N., Lopez-Olmeda, J.F., Foà, A., Berti, R., Sánchez-Vázquez, F.J., Bertolucci, C., and Foulkes, N.S. (2011) A Blind Circadian Clock in Cavefish Reveals that Opsins Mediate Peripheral Clock Photoreception. PLoS Biology. 9(9):e1001142
Vatine, G., Vallone, D., Gothilf, Y., and Foulkes, N.S. (2011) It's time to swim! Zebrafish and the circadian clock. FEBS letters. 585(10):1485-1494
Weger, B.D., Sahinbas, M., Otto, G.W., Mracek, P., Armant, O., Dolle, D., Lahiri, K., Vallone, D., Ettwiller, L., Geisler, R., Foulkes, N.S., and Dickmeis, T. (2011) The light responsive transcriptome of the zebrafish: function and regulation. PLoS One. 6(2):e17080
Ben-Moshe, Z., Vatine, G., Alon, S., Tovin, A., Mracek, P., Foulkes, N.S., and Gothilf, Y. (2010) Multiple PAR and E4BP4 bZIP transcription factors in zebrafish: diverse spatial and temporal expression patterns. Chronobiology International. 27(8):1509-1531
Vatine, G., Vallone, D., Appelbaum, L., Mracek, P., Ben-Moshe, Z., Lahiri, K., Gothilf, Y., and Foulkes, N.S. (2009) Light directs zebrafish period2 expression via conserved D and E boxes. PLoS Biology. 7(10):e1000223
Cossins, A.R., Williams, D.R., Foulkes, N.S., Berenbrink, M., and Kipar, A. (2009) Diverse cell-specific expression of myoglobin isoforms in brain, kidney, gill and liver of the hypoxia-tolerant carp and zebrafish. The Journal of experimental biology. 212(Pt 5):627-638
Dickmeis, T., Lahiri, K., Nica, G., Vallone, D., Santoriello, C., Neumann, C.J., Hammerschmidt, M., and Foulkes, N.S. (2007) Glucocorticoids Play a Key Role in Circadian Cell Cycle Rhythms. PLoS Biology. 5(4):e78
Vallone, D., Santoriello, C., Gondi, S.B., and Foulkes, N.S. (2007) Basic protocols for zebrafish cell lines: Maintenance and transfection. Methods in molecular biology (Clifton, N.J.). 362(1):429-441
Zilberman-Peled, B., Appelbaum, L., Vallone, D., Foulkes, N.S., Anava, S., Anzulovich, A., Coon, S.L., Klein, D.C., Falcon, J., Ron, B., and Gothilf, Y. (2007) Transcriptional regulation of arylalkylamine-N-acetyltransferase-2 gene in the pineal gland of the gilthead seabream. Journal of neuroendocrinology. 19(1):46-53
Appelbaum, L., Vallone, D., Anzulovich, A., Ziv, L., Tom, M., Foulkes, N.S., and Gothilf, Y. (2006) Zebrafish arylalkylamine-N-acetyltransferase genes - targets for regulation of the circadian clock. Journal of molecular endocrinology. 36(2):337-347
Rembold, M., Lahiri, K., Foulkes, N.S., and Wittbrodt, J. (2006) Transgenesis in fish: efficient selection of transgenic fish by co-injection with a fluorescent reporter construct. Nature Protocols. 1(3):1133-1139
Lahiri, K., Vallone, D., Gondi, S.B., Santoriello, C., Dickmeis, T., and Foulkes, N.S. (2005) Temperature Regulates Transcription in the Zebrafish Circadian Clock. PLoS Genetics. 3(11):e351
Vallone, D., Lahiri, K., Dickmeis, T., and Foulkes, N.S. (2005) Zebrafish Cell Clocks Feel the Heat and See the Light!. Zebrafish. 2(3):171-187
Vallone, D., Gondi, S.B., Whitmore, D., and Foulkes, N.S. (2004) E-box function in a period gene repressed by light. Proceedings of the National Academy of Sciences of the United States of America. 101(12):4106-4111
Tamai, T.K., Vardhanabhuti, V., Foulkes, N.S., and Whitmore, D. (2004) Early embryonic light detection improves survival. Current biology : CB. 14(3):R104-105
Dekens, M.P.S., Santoriello, C., Vallone, D., Grassi, G., Whitmore, D., and Foulkes, N.S. (2003) Light regulates the cell cycle in zebrafish. Current biology : CB. 13(23):2051-2057
Tamai, T.K., Vardhanabhuti, V., Arthur, S., Foulkes, N.S., and Whitmore, D. (2003) Flies and fish: birds of a feather. Journal of neuroendocrinology. 15(4):344-349
Whitmore, D., Cermakian, N., Crosio, C., Foulkes, N.S., Pando, M.P., Travnickova, Z., and Sassone-Corsi, P. (2000) A clockwork organ. Biological chemistry. 381(9-10):793-800
Cermakian, N., Whitmore, D., Foulkes, N.S., and Sassone-Corsi, P. (2000) Asynchronous oscillations of two zebrafish CLOCK partners reveal differential clock control and function. Proceedings of the National Academy of Sciences of the United States of America. 97(8):4339-4344
Whitmore, D., Foulkes, N.S., and Sassone-Corsi, P. (2000) Light acts directly on organs and cells in culture to set the vertebrate circadian clock. Nature. 404(6773):87-91
Cermakian, N., Whitmore, D., Foulkes, N.S., and Sassone-Corsi, P. (2000) Independent peripheral clocks and direct light entrainment within the zebrafish circadian system. Journal of molecular medicine (Berlin, Germany). 78(7):B46
Whitmore, D., Foulkes, N.S., Strähle, U., and Sassone-Corsi, P. (1998) Zebrafish Clock rhythmic expression reveals independent peripheral circadian oscillators. Nature Neuroscience. 1(8):701-707

NON-ZEBRAFISH PUBLICATIONS