PUBLICATION
Neurons in the Dorso-Central Division of Zebrafish Pallium Respond to Change in Visual Numerosity
- Authors
- Messina, A., Potrich, D., Schiona, I., Sovrano, V.A., Fraser, S.E., Brennan, C.H., Vallortigara, G.
- ID
- ZDB-PUB-210730-12
- Date
- 2021
- Source
- Cerebral cortex (New York, N.Y. : 1991) 32(2): 418-428 (Journal)
- Registered Authors
- Brennan, Caroline, Fraser, Scott E.
- Keywords
- Danio rerio, Approximate Number System, immediate early genes, number cognition, numerousness, quantity discrimination
- MeSH Terms
-
- Animals
- Cerebral Cortex
- Neurons*/physiology
- Zebrafish*/physiology
- PubMed
- 34322692 Full text @ Cereb. Cortex
Citation
Messina, A., Potrich, D., Schiona, I., Sovrano, V.A., Fraser, S.E., Brennan, C.H., Vallortigara, G. (2021) Neurons in the Dorso-Central Division of Zebrafish Pallium Respond to Change in Visual Numerosity. Cerebral cortex (New York, N.Y. : 1991). 32(2):418-428.
Abstract
We found a region of the zebrafish pallium that shows selective activation upon change in the numerosity of visual stimuli. Zebrafish were habituated to sets of small dots that changed in individual size, position, and density, while maintaining their numerousness and overall surface. During dishabituation tests, zebrafish faced a change in number (with the same overall surface), in shape (with the same overall surface and number), or in size (with the same shape and number) of the dots, whereas, in a control group, zebrafish faced the same stimuli as during the habituation. Modulation of the expression of the immediate early genes c-fos and egr-1 and in situ hybridization revealed a selective activation of the caudal part of the dorso-central division of the zebrafish pallium upon change in numerosity. These findings support the existence of an evolutionarily conserved mechanism for approximate magnitude and provide an avenue for understanding its underlying molecular correlates.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping