PUBLICATION
FaceBase 3: analytical tools and FAIR resources for craniofacial and dental research
- Authors
- Samuels, B.D., Aho, R., Brinkley, J.F., Bugacov, A., Feingold, E., Fisher, S., Gonzalez-Reiche, A.S., Hacia, J.G., Hallgrimsson, B., Hansen, K., Harris, M.P., Ho, T.V., Holmes, G., Hooper, J.E., Jabs, E.W., Jones, K.L., Kesselman, C., Klein, O.D., Leslie, E.J., Li, H., Liao, E.C., Long, H., Lu, N., Maas, R.L., Marazita, M.L., Mohammed, J., Prescott, S., Schuler, R., Selleri, L., Spritz, R.A., Swigut, T., van Bakel, H., Visel, A., Welsh, I., Williams, C., Williams, T.J., Wysocka, J., Yuan, Y., Chai, Y.
- ID
- ZDB-PUB-201002-112
- Date
- 2020
- Source
- Development (Cambridge, England) 147(18): (Journal)
- Registered Authors
- Fisher, Shannon, Harris, Matthew
- Keywords
- Craniofacial development, Data resource, FaceBase Consortium, Human, Mouse, Zebrafish
- MeSH Terms
-
- Animals
- Databases, Factual
- Dental Research/methods*
- Facial Bones/physiology*
- Humans
- Reproducibility of Results
- Research Personnel
- Skull/physiology*
- PubMed
- 32958507 Full text @ Development
Citation
Samuels, B.D., Aho, R., Brinkley, J.F., Bugacov, A., Feingold, E., Fisher, S., Gonzalez-Reiche, A.S., Hacia, J.G., Hallgrimsson, B., Hansen, K., Harris, M.P., Ho, T.V., Holmes, G., Hooper, J.E., Jabs, E.W., Jones, K.L., Kesselman, C., Klein, O.D., Leslie, E.J., Li, H., Liao, E.C., Long, H., Lu, N., Maas, R.L., Marazita, M.L., Mohammed, J., Prescott, S., Schuler, R., Selleri, L., Spritz, R.A., Swigut, T., van Bakel, H., Visel, A., Welsh, I., Williams, C., Williams, T.J., Wysocka, J., Yuan, Y., Chai, Y. (2020) FaceBase 3: analytical tools and FAIR resources for craniofacial and dental research. Development (Cambridge, England). 147(18):.
Abstract
The FaceBase Consortium was established by the National Institute of Dental and Craniofacial Research in 2009 as a 'big data' resource for the craniofacial research community. Over the past decade, researchers have deposited hundreds of annotated and curated datasets on both normal and disordered craniofacial development in FaceBase, all freely available to the research community on the FaceBase Hub website. The Hub has developed numerous visualization and analysis tools designed to promote integration of multidisciplinary data while remaining dedicated to the FAIR principles of data management (findability, accessibility, interoperability and reusability) and providing a faceted search infrastructure for locating desired data efficiently. Summaries of the datasets generated by the FaceBase projects from 2014 to 2019 are provided here. FaceBase 3 now welcomes contributions of data on craniofacial and dental development in humans, model organisms and cell lines. Collectively, the FaceBase Consortium, along with other NIH-supported data resources, provide a continuously growing, dynamic and current resource for the scientific community while improving data reproducibility and fulfilling data sharing requirements.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping