PUBLICATION

Modeling Alzheimer's and Other Age Related Human Diseases in Embryonic Systems

Authors
Lim, C.H., Mathuru, A.S.
ID
ZDB-PUB-180405-4
Date
2017
Source
Journal of developmental biology   6(1): (Other)
Registered Authors
Mathuru, Ajay
Keywords
Alzheimer’s disease, CRY2, Caenorhabditis elegans, Danio rerio, Drosophila melanogaster, optogenetics
MeSH Terms
none
PubMed
29615550 Full text @ J Dev Biol
Abstract
Modeling human disease in animals is an important strategy to discover potential methods of intervention. We suggest that there is much to be gained by employing a multi-model approach that takes advantage of different animal systems used in the laboratory simultaneously. We use the example of modeling Alzheimer's disease in Drosophila melanogaster, Caenorhabditis elegans, and Danio rerio to illustrate how such an approach can be employed to investigate the pathophysiology of the disease.
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