ZFIN ID: ZDB-PUB-161026-4
Transvection Arising from Transgene Interactions in Zebrafish
Keefe, M.D., Bonkowsky, J.L.
Date: 2017
Source: Zebrafish   14(1): 8-9 (Journal)
Registered Authors: Bonkowsky, Joshua, Keefe, Matthew
Keywords: Gal4, UAS, transgenic, transvection, zebrafish
MeSH Terms:
  • Animals
  • Animals, Genetically Modified/genetics*
  • Animals, Genetically Modified/growth & development
  • Animals, Genetically Modified/metabolism
  • Epistasis, Genetic*
  • Gene Expression Regulation
  • Green Fluorescent Proteins/genetics
  • Green Fluorescent Proteins/metabolism*
  • Humans
  • Potassium Channels, Inwardly Rectifying/genetics
  • Potassium Channels, Inwardly Rectifying/metabolism
  • Promoter Regions, Genetic
  • Regulatory Sequences, Nucleic Acid*
  • Transgenes*
  • Zebrafish/genetics*
  • Zebrafish/growth & development
  • Zebrafish/metabolism
PubMed: 27779464 Full text @ Zebrafish
There has been a rapid expansion in use of transgenic technologies in zebrafish. We report a novel example of trans-interactions of genetic elements, or transvection. This interaction led to a novel expression pattern and illustrates a precautionary example regarding use of transgenes in zebrafish.