ZFIN ID: ZDB-PERS-050426-27
Bonkowsky, Joshua
Email: jbonkowsky@gmail.com
Affiliation: Bonkowsky Lab
Address: Department of Neurobiology and Anatomy University of Utah Medical Center 409 Wintrobe 20 North 1900 East Salt Lake City, UT 84132 USA
Country: United States


Son, J.H., Gerenza, A.K., Bingener, G.M., Bonkowsky, J.L. (2022) Hypoplasia of dopaminergic neurons by hypoxia-induced neurotoxicity is associated with disrupted swimming development of larval zebrafish. Frontiers in Cellular Neuroscience. 16:963037
Derksen, A., Shih, H.Y., Forget, D., Darbelli, L., Tran, L.T., Poitras, C., Guerrero, K., Tharun, S., Alkuraya, F.S., Kurdi, W.I., Nguyen, C.E., Laberge, A.M., Si, Y., Gauthier, M.S., Bonkowsky, J.L., Coulombe, B., Bernard, G. (2021) Variants in LSM7 impair LSM complexes assembly, neurodevelopment in zebrafish and may be associated with an ultra-rare neurological disease. HGG advances. 2:100034
Lee, Y.R., Kim, S.H., Ben-Mahmoud, A., Kim, O.H., Choi, T.I., Lee, K.H., Ku, B., Eum, J., Kee, Y., Lee, S., Cha, J., Won, D., Lee, S.T., Choi, J.R., Lee, J.S., Kim, H.D., Kim, H.G., Bonkowsky, J.L., Kang, H.C., Kim, C.H. (2021) Eif2b3 mutants recapitulate phenotypes of Vanishing White Matter Disease and validate novel disease alleles in zebrafish. Human molecular genetics. 30(5):331-342
Son, J.H., Stevenson, T.J., Bowles, M.D., Scholl, E.A., Bonkowsky, J.L. (2020) Dopaminergic Co-Regulation of Locomotor Development and Motor Neuron Synaptogenesis is Uncoupled by Hypoxia in Zebrafish. eNeuro. 7(1):
Gao, J., Stevenson, T.J., Douglass, A.D., Barrios, J.P., Bonkowsky, J.L. (2018) The Midline Axon Crossing Decision Is Regulated through an Activity-Dependent Mechanism by the NMDA Receptor. eNeuro. 5(2)
Lambert, C.J., Freshner, B.C., Chung, A., Stevenson, T.J., Bowles, D.M., Samuel, R., Gale, B.K., Bonkowsky, J.L. (2018) An automated system for rapid cellular extraction from live zebrafish embryos and larvae: Development and application to genotyping. PLoS One. 13:e0193180
Strachan, L.R., Stevenson, T.J., Freshner, B., Keefe, M.D., Miranda Bowles, D., Bonkowsky, J.L. (2017) A zebrafish model of X-linked adrenoleukodystrophy recapitulates key disease features and demonstrates a developmental requirement for abcd1 in oligodendrocyte patterning and myelination. Human molecular genetics. 26:3600-3614
Keefe, M.D., Bonkowsky, J.L. (2017) Transvection Arising from Transgene Interactions in Zebrafish. Zebrafish. 14(1):8-9
Eisenhoffer, G.T., Slattum, G., Ruiz, O.E., Otsuna, H., Bryan, C.D., Lopez, J., Wagner, D.S., Bonkowsky, J.L., Chien, C.B., Dorsky, R.I., Rosenblatt, J. (2017) A toolbox to study epidermal cell types in zebrafish. Journal of Cell Science. 130(1):269-277
Dukes, A.A., Bai, Q., Van Laar, V.S., Zhou, Y., Ilin, V., David, C.N., Agim, Z.S., Bonkowsky, J.L., Cannon, J.R., Watkins, S.C., Croix, C.M., Burton, E.A., Berman, S.B. (2016) Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure. Neurobiology of disease. 95:238-49
Chen, Y.C., Semenova, S., Rozov, S., Sundvik, M., Bonkowsky, J.L., Panula, P. (2016) A novel developmental role for dopaminergic signaling to specify hypothalamic neurotransmitter identity. The Journal of biological chemistry. 291(42):21880-21892
Milash, B., Gao, J., Stevenson, T.J., Son, J.H., Dahl, T., Bonkowsky, J.L. (2016) Temporal Dysynchrony in brain connectivity gene expression following hypoxia. BMC Genomics. 17:334
McPherson, A.D., Barrios, J.P., Luks-Morgan, S.J., Manfredi, J.P., Bonkowsky, J.L., Douglass, A.D., Dorsky, R.I. (2016) Motor Behavior Mediated by Continuously Generated Dopaminergic Neurons in the Zebrafish Hypothalamus Recovers after Cell Ablation. Current biology : CB. 26(2):263-9
Son, J.H., Keefe, M.D., Stevenson, T.J., Barrios, J.P., Anjewierden, S., Newton, J.B., Douglass, A.D., Bonkowsky, J.L. (2016) Transgenic FingRs for Live Mapping of Synaptic Dynamics in Genetically-Defined Neurons. Scientific Reports. 6:18734
Duncan, R.N., Xie, Y., McPherson, A.D., Taibi, A.V., Bonkowsky, J.L., Douglass, A.D., Dorsky, R.I. (2016) Hypothalamic radial glia function as self-renewing neural progenitors in the absence of Wnt/ß-catenin signaling. Development (Cambridge, England). 143(1):45-53
Xing, L., Son, J.H., Stevenson, T.J., Lillesaar, C., Bally-Cuif, L., Dahl, T., Bonkowsky, J.L. (2015) A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:14794-808
Samuel, R., Stephenson, R., Roy, P., Pryor, R., Zhou, L., Bonkowsky, J.L., Gale, B.K. (2015) Microfluidic-aided genotyping of zebrafish in the first 48 h with 100 % viability. Biomedical Microdevices. 17(2):43
Butterfield, R.J., Stevenson, T.J., Xing, L., Newcomb, T.M., Nelson, B., Zeng, W., Li, X., Lu, H.M., Lu, H., Farwell Gonzalez, K.D., Wei, J.P., Chao, E.C., Prior, T.W., Snyder, P.J., Bonkowsky, J.L., Swoboda, K.J. (2014) Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis. Neurology. 82:1322-30
Xing, L., Quist, T.S., Stevenson, T.J., Dahlem, T.J., Bonkowsky, J.L. (2014) Rapid and efficient zebrafish genotyping using PCR with high-resolution melt analysis. Journal of visualized experiments : JoVE. (84):e51138
Iwasaki, K., Taguchi, M., Bonkowsky, J.L., and Kuwada, J.Y. (2013) Expression of Arginine Vasotocin Receptors in the Developing Zebrafish CNS. Gene expression patterns : GEP. 13(8):335-42
Schweitzer, J., Löhr, H., Bonkowsky, J.L., Hübscher, K., and Driever, W. (2013) Sim1a and Arnt2 contribute to hypothalamo-spinal axon guidance by regulating Robo2 activity via a Robo3-dependent mechanism. Development (Cambridge, England). 140(1):93-106
Lambert, A.M., Bonkowsky, J.L., and Masino, M.A. (2012) The conserved dopaminergic diencephalospinal tract mediates vertebrate locomotor development in zebrafish larvae. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(39):13488-13500
Lakhina, V., Marcaccio, C.L., Shao, X., Lush, M.E., Jain, R.A., Fujimoto, E., Bonkowsky, J.L., Granato, M., and Raper, J.A. (2012) Netrin/DCC Signaling Guides Olfactory Sensory Axons to Their Correct Location in the Olfactory Bulb. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(13):4440-4456
Xing, L., Hoshijima, K., Grunwald, D.J., Fujimoto, E., Quist, T.S., Sneddon, J., Chien, C.B., Stevenson, T.J., and Bonkowsky, J.L. (2012) Zebrafish foxP2 Zinc Finger Nuclease Mutant Has Normal Axon Pathfinding. PLoS One. 7(8):e43968
Stevenson, T.J., Trinh, T., Kogelschatz, C., Fujimoto, E., Lush, M.E., Piotrowski, T., Brimley, C.J., and Bonkowsky, J.L. (2012) Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium. PLoS Genetics. 8(4):e1002638
Gutnick, A., Blechman, J., Kaslin, J., Herwig, L., Belting, H.G., Affolter, M., Bonkowsky, J.L., and Levkowitz, G. (2011) The hypothalamic neuropeptide oxytocin is required for formation of the neurovascular interface of the pituitary. Developmental Cell. 21(4):642-654
Fujimoto, E., Gaynes, B., Brimley, C.J., Chien, C.B., and Bonkowsky, J.L. (2011) Gal80 intersectional regulation of cell-type specific expression in vertebrates. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(10):2324-34
Fujimoto, E., Stevenson, T.J., Chien, C.B., and Bonkowsky, J.L. (2011) Identification of a Dopaminergic Enhancer Indicates Complexity in Vertebrate Dopamine Neuron Phenotype Specification. Developmental Biology. 352(2):393-404
Kastenhuber, E., Kern U., Bonkowsky, J.L., Chien, C.B., Driever, W., and Schweitzer, J. (2009) Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(28):8914-8926
Bonkowsky, J.L., Wang, X., Fujimoto, E., Lee, J.E., Chien, C.B., and Dorsky, R.I. (2008) Domain-specific regulation of foxP2 CNS expression by lef1. BMC Developmental Biology. 8:103
Bonkowsky, J.L., and Chien, C.B. (2005) Molecular cloning and developmental expression of foxP2 in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 234(3):740-746