PUBLICATION
Advances in whole-embryo imaging: a quantitative transition is underway
- Authors
- Pantazis, P., Supatto, W.
- ID
- ZDB-PUB-140607-14
- Date
- 2014
- Source
- Nature reviews. Molecular cell biology 15: 327-39 (Review)
- Registered Authors
- Pantazis, Periklis (Laki)
- Keywords
- none
- MeSH Terms
-
- Animals
- Caenorhabditis elegans/anatomy & histology*
- Caenorhabditis elegans/embryology
- Caenorhabditis elegans/genetics
- Drosophila melanogaster/anatomy & histology*
- Drosophila melanogaster/embryology
- Drosophila melanogaster/genetics
- Embryo, Nonmammalian
- Embryonic Development
- Genes, Reporter
- Green Fluorescent Proteins/genetics
- Image Processing, Computer-Assisted/instrumentation
- Image Processing, Computer-Assisted/methods*
- Microscopy, Fluorescence, Multiphoton
- Molecular Imaging/instrumentation
- Molecular Imaging/methods*
- Molecular Probes
- Spectrometry, Fluorescence
- Zebrafish/anatomy & histology*
- Zebrafish/embryology
- Zebrafish/genetics
- PubMed
- 24739741 Full text @ Nat. Rev. Mol. Cell. Biol.
Citation
Pantazis, P., Supatto, W. (2014) Advances in whole-embryo imaging: a quantitative transition is underway. Nature reviews. Molecular cell biology. 15:327-39.
Abstract
With the advent of imaging probes and live microscopy, developmental biologists have markedly extended our understanding of the molecular and cellular details of embryonic development. To fully comprehend the complex mechanistic framework that forms the developing organism, quantitative studies with high fidelity in space and time are now required. We discuss how integrating established, newly introduced and future imaging tools with quantitative analysis will ensure that imaging can fulfil its promise to elucidate how new life begins.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping