ZFIN ID: ZDB-PUB-110613-12
Automated measurement of zebrafish larval movement
Cario, C.L., Farrell, T.C., Milanese, C., and Burton, E.
Date: 2011
Source: The Journal of physiology   589(Pt 15): 3703-8 (Journal)
Registered Authors: Burton, Edward A.
Keywords: motility assay, motion, zebrafish, software
MeSH Terms:
  • Animals
  • Larva
  • Movement/physiology*
  • Software*
  • Video Recording*
  • Zebrafish/physiology*
PubMed: 21646414 Full text @ J. Physiol.
The zebrafish is a powerful vertebrate model that is readily amenable to genetic, pharmacologic and environmental manipulations to elucidate the molecular and cellular basis of movement and behaviour. We report software enabling automated analysis of zebrafish movement from video recordings captured with cameras ranging from a basic camcorder to more specialized equipment. The software, which is provided as open-source Matlab functions, can be freely modified and distributed, and is compatible with multiwell plates under a wide range of experimental conditions. Automated measurement of zebrafish movement using this technique will be useful for multiple applications in neuroscience, pharmacology and neuropsychiatry.