PUBLICATION
Automated measurement of zebrafish larval movement
- Authors
- Cario, C.L., Farrell, T.C., Milanese, C., and Burton, E.
- ID
- ZDB-PUB-110613-12
- Date
- 2011
- Source
- The Journal of physiology 589(Pt 15): 3703-8 (Journal)
- Registered Authors
- Burton, Edward A.
- Keywords
- motility assay, motion, zebrafish, software
- MeSH Terms
-
- Animals
- Larva
- Movement/physiology*
- Software*
- Video Recording*
- Zebrafish/physiology*
- PubMed
- 21646414 Full text @ J. Physiol.
Citation
Cario, C.L., Farrell, T.C., Milanese, C., and Burton, E. (2011) Automated measurement of zebrafish larval movement. The Journal of physiology. 589(Pt 15):3703-8.
Abstract
The zebrafish is a powerful vertebrate model that is readily amenable to genetic, pharmacologic and environmental manipulations to elucidate the molecular and cellular basis of movement and behaviour. We report software enabling automated analysis of zebrafish movement from video recordings captured with cameras ranging from a basic camcorder to more specialized equipment. The software, which is provided as open-source Matlab functions, can be freely modified and distributed, and is compatible with multiwell plates under a wide range of experimental conditions. Automated measurement of zebrafish movement using this technique will be useful for multiple applications in neuroscience, pharmacology and neuropsychiatry.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping