ZFIN ID: ZDB-PERS-080122-4
Burton, Edward A.
Email: eab25+@pitt.edu
Affiliation: Burton Lab
Address: University of Pittsburgh School of Medicine Pittsburgh Institute for Neurodegenerative Diseases 7015 BST-3 3501 Fifth Avenue Pittsburgh, PA 15261 USA
Country: United States
Phone: 412 648 8480
Fax: 412 648 9082


Hossainian, D., Shao, E., Jiao, B., Ilin, V.A., Parris, R.S., Zhou, Y., Bai, Q., Burton, E.A. (2022) Quantification of functional recovery in a larval zebrafish model of spinal cord injury. Journal of neuroscience research. 100(11):2044-2054
Burton, A.H., Bai, Q., Burton, E.A. (2021) Sinusoidal analysis reveals a non-linear and dopamine-dependent relationship between ambient illumination and motor activity in larval zebrafish. Neuroscience letters. 761:136121
Ilin, V.A., Bai, Q., Watson, A.M., Volgushev, M., Burton, E.A. (2021) Mechanism of pacemaker activity in zebrafish DC2/4 dopaminergic neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. 41(18):4141-4157
Alyenbaawi, H., Kanyo, R., Locskai, L.F., Kamali-Jamil, R., DuVal, M.G., Bai, Q., Wille, H., Burton, E.A., Allison, W.T. (2021) Seizures are a druggable mechanistic link between TBI and subsequent tauopathy. eLIFE. 10:
Van Laar, V.S., Chen, J., Zharikov, A.D., Bai, Q., Di Maio, R., Dukes, A.A., Hastings, T.G., Watkins, S.C., Greenamyre, J.T., St Croix, C.M., Burton, E.A. (2020) α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo. Redox Biology. 37:101695
Xie, W., Jiao, B., Bai, Q., Ilin, V.A., Sun, M., Burton, C.E., Kolodieznyi, D., Calderon, M.J., Stolz, D.B., Opresko, P.L., St Croix, C.M., Watkins, S., Van Houten, B., Bruchez, M.P., Burton, E.A. (2020) Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity. eLIFE. 9:
Watson, L., Keatinge, M., Gegg, M., Bai, Q., Sandulescu, C., Vardi, A., Futerman, A.H., Schapira, A.H.V., Burton, E.A., Bandmann, O. (2019) Ablation of the pro-inflammatory master regulator miR-155 does not mitigate neuroinflammation or neurodegeneration in a vertebrate model of Gaucher's disease. Neurobiology of disease. 127:563-569
Hanovice, N.J., Leach, L.L., Slater, K., Gabriel, A.E., Romanovicz, D., Shao, E., Collery, R., Burton, E.A., Lathrop, K.L., Link, B.A., Gross, J.M. (2019) Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation. PLoS Genetics. 15:e1007939
Frøyset, A.K., Edson, A.J., Gharbi, N., Khan, E.A., Dondorp, D., Bai, Q., Tiraboschi, E., Suster, M.L., Connolly, J.B., Burton, E.A., Fladmark, K.E. (2018) Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo. Redox Biology. 16:237-247
Shao, E., Scheetz, S.D., Xie, W., Burton, E.A. (2018) Modulation of the zebrafish optokinetic reflex by pharmacologic agents targeting GABAA receptors.. Neuroscience letters. 671:33-37
Scheetz, S.D., Shao, E., Zhou, Y., Cario, C.L., Bai, Q., Burton, E.A. (2017) An open-source method to analyze optokinetic reflex responses in larval zebrafish. Journal of Neuroscience Methods. 293:329-337
Shao, E., Bai, Q., Zhou, Y., Burton, E.A. (2017) Quantitative Responses of Adult Zebrafish to Changes in Ambient Illumination. Zebrafish. 14(6):508-516
Burton, C.E., Zhou, Y., Bai, Q., Burton, E.A. (2017) Spectral properties of the zebrafish visual motor response. Neuroscience letters. 646:62-67
Dukes, A.A., Bai, Q., Van Laar, V.S., Zhou, Y., Ilin, V., David, C.N., Agim, Z.S., Bonkowsky, J.L., Cannon, J.R., Watkins, S.C., Croix, C.M., Burton, E.A., Berman, S.B. (2016) Live imaging of mitochondrial dynamics in CNS dopaminergic neurons in vivo demonstrates early reversal of mitochondrial transport following MPP(+) exposure. Neurobiology of disease. 95:238-49
Mahoney, S., Najera, M., Bai, Q., Burton, E.A., Veser, G. (2016) The Developmental Toxicity of Complex Silica-Embedded Nickel Nanoparticles Is Determined by Their Physicochemical Properties. PLoS One. 11:e0152010
Keatinge, M., Bui, H., Menke, A., Chen, Y.C., Sokol, A.M., Bai, Q., Ellett, F., Da Costa, M., Burke, D., Gegg, M., Trollope, L., Payne, T., McTighe, A., Mortiboys, H., de Jager, S., Nuthhall, H., Kuo, M.S., Fleming, A., Schapira, A.H., Renshaw, S.A., Highley, J.R., Chacinska, A., Panula, P., Burton, E.A., O'Neill, M.J., Bandmann, O. (2015) Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death. Human molecular genetics. 24(23):6640-52
Bai, Q., Parris, R.S., Burton, E.A. (2014) Different Mechanisms Regulate Expression of Zebrafish Myelin Protein Zero (P0) in Myelinating Oligodendrocytes and Its Induction following Axonal Injury. The Journal of biological chemistry. 289(35):24114-28
Zhou, Y., Cattley, R.T., Cario, C.L., Bai, Q., Burton, E.A. (2014) Quantification of larval zebrafish motor function in multiwell plates using open-source MATLAB applications. Nature Protocols. 9:1533-1548
Münzel, E.J., Schaefer, K., Obirei, B., Kremmer, E., Burton, E.A., Kuscha, V., Becker, C.G., Brösamle, C., Williams, A., and Becker, T. (2012) Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish. Glia. 60(2):253-70
Milanese, C., Sager, J.J., Bai, Q., Farrell, T.C., Cannon, J.R., Greenamyre, J.T., and Burton, E.A. (2012) Hypokinesia and reduced dopamine levels in zebrafish lacking beta- and gamma1-synucleins. The Journal of biological chemistry. 287(5):2971-2983
Sager, J.J., Torres, G.E., and Burton, E.A. (2012) The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development. PLoS One. 7(9):e45175
Farrell, T.C., Cario, C.L., Milanese, C., Vogt, A., Jeong, J.H., and Burton, E.A. (2011) Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models. Neurobiology of disease. 44(1):9-18
Horowitz, M., Milanese, C., Di Maio, R., Hu, X., Montero, L.M., Sanders, L.H., Tapias, V., Sepe, S., van Capellen, W.A., Burton, E.A., Greenamyre, T., and Mastroberardino, P.G. (2011) Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults. Antioxidants & redox signaling. 15(4):855-71
Cario, C.L., Farrell, T.C., Milanese, C., and Burton, E. (2011) Automated measurement of zebrafish larval movement. The Journal of physiology. 589(Pt 15):3703-8
Bai, Q., Sun, M., Stolz, D.B., and Burton, E.A. (2011) Major isoform of zebrafish P0 is a 23.5 kDa myelin glycoprotein expressed in selected white matter tracts of the central nervous system. The Journal of comparative neurology. 519(8):1580-1596
Bai, Q., and Burton, E.A. (2011) Zebrafish models of Tauopathy. Biochimica et biophysica acta. Molecular basis of disease. 1812(3):353-363
Bandmann, O., and Burton, E.A. (2010) Genetic zebrafish models of neurodegenerative diseases. Neurobiology of disease. 40(1):58-65
Sager, J.J., Bai, Q., and Burton, E.A. (2010) Transgenic zebrafish models of neurodegenerative diseases. Brain structure & function. 214(2-3):285-302
Bai, Q., and Burton, E.A. (2009) Cis-acting elements responsible for dopaminergic neuron-specific expression of zebrafish slc6a3 (dopamine transporter) in vivo are located remote from the transcriptional start site. Neuroscience. 164(3):1138-1151
Bai, Q., Wei, X., and Burton, E.A. (2009) Expression of a 12-kb promoter element derived from the zebrafish enolase-2 gene in the zebrafish visual system. Neuroscience letters. 449(3):252-257
Bai, Q., Garver, J.A., Hukriede, N.A., and Burton, E.A. (2007) Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene. Nucleic acids research. 35(19):6501-6516
Bai, Q., Mullett, S.J., Garver, J.A., Hinkle, D.A., and Burton, E.A. (2006) Zebrafish DJ-1 is evolutionarily conserved and expressed in dopaminergic neurons. Brain research. 1113(1):33-44