PUBLICATION
Sp1-like transcription factors are regulators of embryonic development in vertebrates
- Authors
- Zhao, C., and Meng, A.
- ID
- ZDB-PUB-071016-1
- Date
- 2005
- Source
- Development, growth & differentiation 47(4): 2001-211 (Review)
- Registered Authors
- Meng, Anming, Zhao, Chengtian
- Keywords
- none
- MeSH Terms
-
- Animals
- Embryonic Development/genetics*
- Sp1 Transcription Factor/physiology*
- Transcription Factors/physiology*
- Vertebrates/embryology*
- Vertebrates/genetics
- PubMed
- 15921495 Full text @ Dev. Growth Diff.
Citation
Zhao, C., and Meng, A. (2005) Sp1-like transcription factors are regulators of embryonic development in vertebrates. Development, growth & differentiation. 47(4):2001-211.
Abstract
Sp1-like family is an expanding transcription factor family. Members of this family bind to the GC-box or GT-box elements in the promoter/enhancers and regulate the expression of the target genes. Currently, this family consists of at least nine members, which may act as a transactivator or a repressor on target promoters. Sp1-like transcription factors are expressed during development of vertebrate embryos in ubiquitous or tissue-specific manners and play various roles in embryonic development. This review mainly summarises their expression patterns and functions during vertebrate embryogenesis.
Genes / Markers
Expression
Phenotype
Mutations / Transgenics
Human Disease / Model
Sequence Targeting Reagents
Fish
Orthology
Engineered Foreign Genes
Mapping