ZFIN ID: ZDB-PUB-001205-2
Vertebrate development: The fast track to Nodal signalling
Stemple, D.L.
Date: 2000
Source: Current biology : CB   10(22): R843-R846 (Review)
Registered Authors: Stemple, Derek L.
Keywords: none
MeSH Terms:
  • Animals
  • DNA-Binding Proteins/genetics
  • DNA-Binding Proteins/metabolism
  • DNA-Binding Proteins/physiology*
  • Forkhead Transcription Factors
  • GPI-Linked Proteins
  • Homeodomain Proteins/genetics
  • Homeodomain Proteins/metabolism
  • Homeodomain Proteins/physiology*
  • Intercellular Signaling Peptides and Proteins
  • Mutagenesis
  • Nodal Protein
  • Signal Transduction/physiology*
  • Transcription Factors/genetics
  • Transcription Factors/metabolism
  • Transcription Factors/physiology*
  • Transforming Growth Factor beta/metabolism*
  • Transforming Growth Factor beta/physiology
  • Xenopus Proteins*
  • Zebrafish/embryology*
  • Zebrafish Proteins*
PubMed: 11102828 Full text @ Curr. Biol.
The transcription factors Fast-1 and Mixer are important terminal components of Smad2-mediated TGF-beta signal transduction. Recent studies demonstrate that Fast-1 and Mixer play critical roles in the formation of endoderm and dorsal mesoderm in zebrafish.