ZFIN ID: ZDB-PERS-970123-4
Stemple, Derek L.
Email: notochord@gmail.com
URL: http://www.sanger.ac.uk/Teams/Team31/
Affiliation: Sanger Centre Zebrafish Project
and also: Stemple Lab
Address: Vertebrate Development and Genetics (Team 31) Wellcome Trust Sanger Institute Wellcome Trust Genome Campus Hinxton Cambridge, CB10 1SA United Kingdom
Country: United Kingdom
Phone: +44 (0)1223 496857
Fax: +44 (0)1223 494919


García-González, J., Brock, A.J., Parker, M.O., Riley, R.J., Joliffe, D., Sudwarts, A., Teh, M.T., Busch-Nentwich, E.M., Stemple, D.L., Martineau, A.R., Kaprio, J., Palviainen, T., Kuan, V., Walton, R.T., Brennan, C.H. (2020) Identification of slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour. eLIFE. 9:
Dooley, C.M., Wali, N., Sealy, I.M., White, R.J., Stemple, D.L., Collins, J.E., Busch-Nentwich, E.M. (2019) The gene regulatory basis of genetic compensation during neural crest induction. PLoS Genetics. 15:e1008213
Camargo-Sosa, K., Colanesi, S., Müller, J., Schulte-Merker, S., Stemple, D., Patton, E.E., Kelsh, R.N. (2019) Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependent pigment progenitors in zebrafish. PLoS Genetics. 15:e1007941
White, R.J., Collins, J.E., Sealy, I.M., Wali, N., Dooley, C.M., Digby, Z., Stemple, D.L., Murphy, D.N., Billis, K., Hourlier, T., Füllgrabe, A., Davis, M.P., Enright, A.J., Busch-Nentwich, E.M. (2017) A high-resolution mRNA expression time course of embryonic development in zebrafish. eLIFE. 6
Henke, K., Daane, J.M., Hawkins, M.B., Dooley, C.M., Busch-Nentwich, E.M., Stemple, D.L., Harris, M.P. (2017) Genetic Screen for Postembryonic Development in the Zebrafish (Danio rerio): Dominant Mutations Affecting Adult Form.. Genetics. 207(2):609-623
Scahill, C.M., Digby, Z., Sealy, I.M., White, R.J., Collins, J.E., Busch-Nentwich, E.M. (2017) The age of heterozygous telomerase mutant parents influences the adult phenotype of their offspring irrespective of genotype in zebrafish.. Wellcome open research. 2:77
Scahill, C.M., Digby, Z., Sealy, I.M., Wojciechowska, S., White, R.J., Collins, J.E., Stemple, D.L., Bartke, T., Mathers, M.E., Patton, E.E., Busch-Nentwich, E.M. (2017) Loss of the chromatin modifier Kdm2aa causes BrafV600E-independent spontaneous melanoma in zebrafish. PLoS Genetics. 13:e1006959
Nelson, A.C., Cutty, S.J., Gasiunas, S.N., Deplae, I., Stemple, D.L., Wardle, F.C. (2017) In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors. Cell Reports. 19:2782-2795
McConnell, S.C., Hernandez, K.M., Wcisel, D.J., Kettleborough, R.N., Stemple, D.L., Yoder, J.A., Andrade, J., de Jong, J.L. (2016) Alternative haplotypes of antigen processing genes in zebrafish diverged early in vertebrate evolution. Proceedings of the National Academy of Sciences of the United States of America. 113(34):E5014-23
Praissman, J.L., Willer, T., Sheikh, M.O., Toi, A., Chitayat, D., Lin, Y.Y., Lee, H., Stalnaker, S.H., Wang, S., Prabhakar, P.K., Nelson, S.F., Stemple, D.L., Moore, S.A., Moremen, K.W., Campbell, K.P., Wells, L. (2016) The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition. eLIFE. 5
Brocal, I., White, R.J., Dooley, C.M., Carruthers, S.N., Clark, R., Hall, A., Busch-Nentwich, E.M., Stemple, D.L., Kettleborough, R.N. (2016) Efficient identification of CRISPR/Cas9-induced insertions/deletions by direct germline screening in zebrafish. BMC Genomics. 17:259
Bielczyk-Maczyńska, E., Lam Hung, L., Ferreira, L., Fleischmann, T., Weis, F., Fernández-Pevida, A., Harvey, S.A., Wali, N., Warren, A.J., Barroso, I., Stemple, D.L., Cvejic, A. (2015) The Ribosome Biogenesis Protein Nol9 Is Essential for Definitive Hematopoiesis and Pancreas Morphogenesis in Zebrafish. PLoS Genetics. 11:e1005677
Sztal, T.E., Zhao, M., Williams, C., Oorschot, V., Parslow, A.C., Giousoh, A., Yuen, M., Hall, T.E., Costin, A., Ramm, G., Bird, P.I., Busch-Nentwich, E.M., Stemple, D.L., Currie, P.D., Cooper, S.T., Laing, N.G., Nowak, K.J., Bryson-Richardson, R.J. (2015) Zebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function. Acta Neuropathologica. 130(3):389-406
Collins, J.E., Wali, N., Sealy, I.M., Morris, J.A., White, R.J., Leonard, S.R., Jackson, D.K., Jones, M.C., Smerdon, N.C., Zamora, J., Dooley, C.M., Carruthers, S.N., Barrett, J.C., Stemple, D.L., Busch-Nentwich, E.M. (2015) High-throughput and quantitative genome-wide messenger RNA sequencing for molecular phenotyping. BMC Genomics. 16:578
Lorent, K., Gong, W., Koo, K.A., Waisbourd-Zinman, O., Karjoo, S., Zhao, X., Sealy, I., Kettleborough, R.N., Stemple, D.L., Windsor, P.A., Whittaker, S.J., Porter, J.R., Wells, R.G., Pack, M. (2015) Identification of a plant isoflavonoid that causes biliary atresia. Science Translational Medicine. 7:286ra67
Kenyon, E.J., Campos, I., Bull, J.C., Williams, P.H., Stemple, D.L., Clark, M.D. (2015) Zebrafish Rab5 Proteins and a role for Rab5ab in nodal signalling. Developmental Biology. 397(2):212-24
Nelson, A.C., Cutty, S.J., Niini, M., Stemple, D.L., Flicek, P., Houart, C., Bruce, A., Wardle, F.C. (2014) Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression. BMC Biology. 12:81
Bielczyk-Maczyńska, E., Serbanovic-Canic, J., Ferreira, L., Soranzo, N., Stemple, D.L., Ouwehand, W.H., Cvejic, A. (2014) A loss of function screen of identified genome-wide association study Loci reveals new genes controlling hematopoiesis. PLoS Genetics. 10:e1004450
Osborn, D.P., Roccasecca, R.M., McMurray, F., Hernandez-Hernandez, V., Mukherjee, S., Barroso, I., Stemple, D., Cox, R., Beales, P.L., and Christou-Savina, S. (2014) Loss of FTO antagonises Wnt signaling and leads to developmental defects associated with ciliopathies. PLoS One. 9(2):e87662
Yen, J., White, R.M., Stemple, D.L. (2014) Zebrafish models of cancer: progress and future challenges. Current opinion in genetics & development. 24C:38-45
Seth, A., Stemple, D.L., and Barroso, I. (2013) The emerging use of zebrafish to model metabolic disease. Disease models & mechanisms. 6(5):1080-1088
Dooley, C.M., Scahill, C., Fényes, F., Kettleborough, R.N., Stemple, D.L., and Busch-Nentwich, E.M. (2013) Multi-allelic phenotyping - A systematic approach for the simultaneous analysis of multiple induced mutations. Methods (San Diego, Calif.). 62(3):197-206
Armant, O., März, M., Schmidt, R., Ferg, M., Diotel, N., Ertzer, R., Bryne, J.C., Yang, L., Baader, I., Reischl, M., Legradi, J., Mikut, R., Stemple, D., Ijcken, W.V., van der Sloot, A., Lenhard, B., Strähle, U., and Rastegar, S. (2013) Genome-wide, whole mount in situ analysis of transcriptional regulators in zebrafish embryos. Developmental Biology. 380(2):351-62
Carss, K.J., Stevens, E., Foley, A.R., Cirak, S., Riemersma, M., Torelli, S., Hoischen, A., Willer, T., van Scherpenzeel, M., Moore, S.A., Messina, S., Bertini, E., Bönnemann, C.G., Abdenur, J.E., Grosmann, C.M., Kesari, A., Punetha, J., Quinlivan, R., Waddell, L.B., Young, H.K., Wraige, E., Yau, S., Brodd, L., Feng, L., Sewry, C., Macarthur, D.G., North, K.N., Hoffman, E., Stemple, D.L., Hurles, M.E., van Bokhoven, H., Campbell, K.P., Lefeber, D.J., Lin, Y.Y., and Muntoni, F. (2013) Mutations in GDP-Mannose Pyrophosphorylase B Cause Congenital and Limb-Girdle Muscular Dystrophies Associated with Hypoglycosylation of alpha-Dystroglycan. American journal of human genetics. 93(1):29-41
Harvey, S.A., Sealy, I., Kettleborough, R., Fenyes, F., White, R., Stemple, D., and Smith, J.C. (2013) Identification of the zebrafish maternal and paternal transcriptomes. Development (Cambridge, England). 140(13):2703-2710
Cvejic, A., Haer-Wigman, L., Stephens, J.C., Kostadima, M., Smethurst, P.A., Frontini, M., van den Akker, E., Bertone, P., Bielczyk-MaczyDska, E., Farrow, S., Fehrmann, R.S., Gray, A., de Haas, M., Haver, V.G., Jordan, G., Karjalainen, J., Kerstens, H.H., Kiddle, G., Lloyd-Jones, H., Needs, M., Poole, J., Soussan, A.A., Rendon, A., Rieneck, K., Sambrook, J.G., Schepers, H., Silljé, H.H., Sipos, B., Swinkels, D., Tamuri, A.U., Verweij, N., Watkins, N.A., Westra, H.J., Stemple, D., Franke, L., Soranzo, N., Stunnenberg, H.G., Goldman, N., van der Harst, P., van der Schoot, C.E., Ouwehand, W.H., and Albers, C.A. (2013) SMIM1 underlies the Vel blood group and influences red blood cell traits. Nature Genetics. 45(5):542-5
Buysse, K., Riemersma, M., Powell, G., van Reeuwijk, J., Chitayat, D., Roscioli, T., Kamsteeg, E.J., van den Elzen, C., van Beusekomm, E., Blaser, S., Babul-Hirji, R., Halliday, W., Wright, G.J., Stemple, D.L., Lin, Y.Y., Lefeber, D.J., and van Bokhoven, H. (2013) Missense mutations in beta-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) cause Walker-Warburg syndrome. Human molecular genetics. 22(9):1746-1754
Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.
Howe, K., Clark, M.D., Torroja, C.F., Torrance, J., Berthelot, C., Muffato, M., Collins, J.E., Humphray, S., McLaren, K., Matthews, L., McLaren, S., Sealy, I., Caccamo, M., Churcher, C., Scott, C., Barrett, J.C., Koch, R., Rauch, G.J., White, S., Chow, W., Kilian, B., Quintais, L.T., Guerra-Assunção, J.A., Zhou, Y., Gu, Y., Yen, J., Vogel, J.H., Eyre, T., Redmond, S., Banerjee, R., Chi, J., Fu, B., Langley, E., Maguire, S.F., Laird, G.K., Lloyd, D., Kenyon, E., Donaldson, S., Sehra, H., Almeida-King, J., Loveland, J., Trevanion, S., Jones, M., Quail, M., Willey, D., Hunt, A., Burton, J., Sims, S., McLay, K., Plumb, B., Davis, J., Clee, C., Oliver, K., Clark, R., Riddle, C., Eliott, D., Threadgold, G., Harden, G., Ware, D., Mortimer, B., Kerry, G., Heath, P., Phillimore, B., Tracey, A., Corby, N., Dunn, M., Johnson, C., Wood, J., Clark, S., Pelan, S., Griffiths, G., Smith, M., Glithero, R., Howden, P., Barker, N., Stevens, C., Harley, J., Holt, K., Panagiotidis, G., Lovell, J., Beasley, H., Henderson, C., Gordon, D., Auger, K., Wright, D., Collins, J., Raisen, C., Dyer, L., Leung, K., Robertson, L., Ambridge, K., Leongamornlert, D., McGuire, S., Gilderthorp, R., Griffiths, C., Manthravadi, D., Nichol, S., Barker, G., Whitehead, S., Kay, M., Brown, J., Murnane, C., Gray, E., Humphries, M., Sycamore, N., Barker, D., Saunders, D., Wallis, J., Babbage, A., Hammond, S., Mashreghi-Mohammadi, M., Barr, L., Martin, S., Wray, P., Ellington, A., Matthews, N., Ellwood, M., Woodmansey, R., Clark, G., Cooper, J., Tromans, A., Grafham, D., Skuce, C., Pandian, R., Andrews, R., Harrison, E., Kimberley, A., Garnett, J., Fosker, N., Hall, R., Garner, P., Kelly, D., Bird, C., Palmer, S., Gehring, I., Berger, A., Dooley, C.M., Ersan-Ürün, Z., Eser, C., Geiger, H., Geisler, M., Karotki, L., Kirn, A., Konantz, J., Konantz, M., Oberländer, M., Rudolph-Geiger, S., Teucke, M., Osoegawa, K., Zhu, B., Rapp, A., Widaa, S., Langford, C., Yang, F., Carter, N.P., Harrow, J., Ning, Z., Herrero, J., Searle, S.M., Enright, A., Geisler, R., Plasterk, R.H., Lee, C., Westerfield, M., de Jong, P.J., Zon, L.I., Postlethwait, J.H., Nüsslein-Volhard, C., Hubbard, T.J., Crollius, H.R., Rogers, J., and Stemple, D.L. (2013) The zebrafish reference genome sequence and its relationship to the human genome. Nature. 496:498-503
Kettleborough, R.N., Busch-Nentwich, E.M., Harvey, S.A., Dooley, C.M., de Bruijn, E., van Eeden, F., Sealy, I., White, R.J., Herd, C., Nijman, I.J., Fényes, F., Mehroke, S., Scahill, C., Gibbons, R., Wali, N., Carruthers, S., Hall, A., Yen, J., Cuppen, E., and Stemple, D.L. (2013) A systematic genome-wide analysis of zebrafish protein-coding gene function. Nature. 496(7446):494-7
Gronskov, K., Dooley, C.M., Ostergaard, E., Kelsh, R.N., Hansen, L., Levesque, M.P., Vilhelmsen, K., Mollgard, K., Stemple, D.L., and Rosenberg, T. (2013) Mutations in C10orf11, a Melanocyte-Differentiation Gene, Cause Autosomal-Recessive Albinism. American journal of human genetics. 92(3):415-421
Stevens, E., Carss, K.J., Cirak, S., Foley, A.R., Torelli, S., Willer, T., Tambunan, D.E., Yau, S., Brodd, L., Sewry, C.A., Feng, L., Haliloglu, G., Orhan, D., Dobyns, W.B., Enns, G.M., Manning, M., Krause, A., Salih, M.A., Walsh, C.A., Hurles, M., Campbell, K.P., Manzini, M.C., Stemple, D., Lin, Y.Y., and Muntoni, F. (2013) Mutations in B3GALNT2 Cause Congenital Muscular Dystrophy and Hypoglycosylation of alpha-Dystroglycan. American journal of human genetics. 92(3):354-365
Patowary, A., Purkanti, R., Singh, M., Chauhan, R., Singh, A.R., Swarnkar, M., Singh, N., Pandey, V., Torroja, C., Clark, M.D., Kocher, J.P., Clark, K.J., Stemple, D.L., Klee, E.W., Ekker, S.C., Scaria, V., and Sivasubbu, S. (2013) A sequence-based variation map of zebrafish. Zebrafish. 10(1):15-20
Yen, J., White, R.M., Wedge, D.C., Van Loo, P., de Ridder, J., Capper, A., Richardson, J., Jones, D., Raine, K., Watson, I.R., Wu, C.J., Cheng, J., Martincorena, I., Nik-Zainal, S., Mudie, L., Moreau, Y., Marshall, J., Ramakrishna, M., Tarpey, P., Shlien, A., Whitmore, I., Gamble, S., Latimer, C., Langdon, E., Kaufman, C., Dovey, M., Taylor, A., Menzies, A., McLaren, S., O Meara, S., Butler, A., Teague, J., Lister, J., Chin, L., Campbell, P., Adams, D.J., Zon, L.I., Patton, E.E., Stemple, D.L., and Futreal, P.A. (2013) The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models. Genome biology. 14(10):R113
Collins, J.E., White, S., Searle, S.M., and Stemple, D.L. (2012) Incorporating RNA-seq data into the Zebrafish Ensembl Gene Build. Genome research. 22(10):2067-2078
Brieu, N., Navab, N., Serbanovic-Canic, J., Ouwehand, W.H., Stemple, D.L., Cvejic, A., and Groher, M. (2012) Image-based characterization of thrombus formation in time-lapse DIC microscopy. Medical image analysis. 16(4):915-931
Roscioli, T., Kamsteeg, E.J., Buysse, K., Maystadt, I., van Reeuwijk, J., van den Elzen, C., van Beusekom, E., Riemersma, M., Pfundt, R., Vissers, L.E., Schraders, M., Altunoglu, U., Buckley, M.F., Brunner, H.G., Grisart, B., Zhou, H., Veltman, J.A., Gilissen, C., Mancini, G.M., Delrée, P., Willemsen, M.A., Ramadža, D.P., Chitayat, D., Bennett, C., Sheridan, E., Peeters, E.A., Tan-Sindhunata, G.M., de Die-Smulders, C.E., Devriendt, K., Kayserili, H., El-Hashash, O.A., Stemple, D.L., Lefeber, D.J., Lin, Y.Y., and van Bokhoven, H. (2012) Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of alpha-dystroglycan. Nature Genetics. 44(5):581-585
Busch-Nentwich, E., Kettleborough, R., Harvey, S., Collins, J., Ding, M., Dooley, C., Fenyes, F., Gibbons, R., Herd, C., Mehroke, S., Scahill, C., Sealy, I., Wali, N., White, R., and Stemple, D.L. (2012) Sanger Institute Zebrafish Mutation Project mutant, phenotype and image data submission. ZFIN Direct Data Submission.
Otten, C., van der Ven, P.F., Lewrenz, I., Paul, S., Steinhagen, A., Busch-Nentwich, E., Eichhorst, J., Wiesner, B., Stemple, D., Strähle, U., Fürst, D.O., and Abdelilah-Seyfried, S. (2012) Xirp proteins mark injured skeletal muscle in zebrafish. PLoS One. 7(2):e31041
Gieger, C., Radhakrishnan, A., Cvejic, A., Tang, W., Porcu, E., Pistis, G., Serbanovic-Canic, J., Elling, U., Goodall, A.H., Labrune, Y., Lopez, L.M., Mägi, R., Meacham, S., Okada, Y., Pirastu, N., Sorice, R., Teumer, A., Voss, K., Zhang, W., Ramirez-Solis, R., Bis, J.C., Ellinghaus, D., Gögele, M., Hottenga, J.J., Langenberg, C., Kovacs, P., O'Reilly, P.F., Shin, S.Y., Esko, T., Hartiala, J., Kanoni, S., Murgia, F., Parsa, A., Stephens, J., van der Harst, P., Ellen van der Schoot, C., Allayee, H., Attwood, A., Balkau, B., Bastardot, F., Basu, S., Baumeister, S.E., Biino, G., Bomba, L., Bonnefond, A., Cambien, F., Chambers, J.C., Cucca, F., D'Adamo, P., Davies, G., de Boer, R.A., de Geus, E.J., Döring, A., Elliott, P., Erdmann, J., Evans, D.M., Falchi, M., Feng, W., Folsom, A.R., Frazer, I.H., Gibson, Q.D., Glazer, N.L., Hammond, C., Hartikainen, A.L., Heckbert, S.R., Hengstenberg, C., Hersch, M., Illig, T., Loos, R.J., Jolley, J., Khaw, K.T., Kühnel, B., Kyrtsonis, M.C., Lagou, V., Lloyd-Jones, H., Lumley, T., Mangino, M., Maschio, A., Mateo Leach, I., McKnight, B., Memari, Y., Mitchell, B.D., Montgomery, G.W., Nakamura, Y., Nauck, M., Navis, G., Nöthlings, U., Nolte, I.M., Porteous, D.J., Pouta, A., Pramstaller, P.P., Pullat, J., Ring, S.M., Rotter, J.I., Ruggiero, D., Ruokonen, A., Sala, C., Samani, N.J., Sambrook, J., Schlessinger, D., Schreiber, S., Schunkert, H., Scott, J., Smith, N.L., Snieder, H., Starr, J.M., Stumvoll, M., Takahashi, A., Tang, W.H., Taylor, K., Tenesa, A., Lay Thein, S., Tönjes, A., Uda, M., Ulivi, S., van Veldhuisen, D.J., Visscher, P.M., Völker, U., Wichmann, H.E., Wiggins, K.L., Willemsen, G., Yang, T.P., Hua Zhao, J., Zitting, P., Bradley, J.R., Dedoussis, G.V., Gasparini, P., Hazen, S.L., Metspalu, A., Pirastu, M., Shuldiner, A.R., Joost van Pelt, L., Zwaginga, J.J., Boomsma, D.I., Deary, I.J., Franke, A., Froguel, P., Ganesh, S.K., Jarvelin, M.R., Martin, N.G., Meisinger, C., Psaty, B.M., Spector, T.D., Wareham, N.J., Akkerman, J.W., Ciullo, M., Deloukas, P., Greinacher, A., Jupe, S., Kamatani, N., Khadake, J., Kooner, J.S., Penninger, J., Prokopenko, I., Stemple, D., Toniolo, D., Wernisch, L., Sanna, S., Hicks, A.A., Rendon, A., Ferreira, M.A., Ouwehand, W.H., Soranzo, N. (2011) New gene functions in megakaryopoiesis and platelet formation. Nature. 480:201-8
Whiteley, A.R., Bhat, A., Martins, E.P., Mayden, R.L., Arunachalam, M., Uusi-Heikkilä, S., Ahmed, A.T., Shrestha, J., Clark, M., Stemple, D., and Bernatchez, L. (2011) Population genomics of wild and laboratory zebrafish (Danio rerio). Molecular Ecology. 20(20):4259-4276
Tijssen, M.R., Cvejic, A., Joshi, A., Hannah, R.L., Ferreira, R., Forrai, A., Bellissimo, D.C., Oram, S.H., Smethurst, P.A., Wilson, N.K., Wang, X., Ottersbach, K., Stemple, D.L., Green, A.R., Ouwehand, W.H., and Göttgens, B. (2011) Genome-wide Analysis of Simultaneous GATA1/2, RUNX1, FLI1, and SCL Binding in Megakaryocytes Identifies Hematopoietic Regulators. Developmental Cell. 20(5):597-609
Lin, Y.Y., White, R.J., Torelli, S., Cirak, S., Muntoni, F., and Stemple, D.L. (2011) Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathies. Human molecular genetics. 20(9):1763-75
Ferrante, M.I., Kiff, R.M., Goulding, D.A., and Stemple, D.L. (2011) Troponin T is essential for sarcomere assembly in zebrafish skeletal muscle. Journal of Cell Science. 124(Pt 4):565-577
Cvejic, A., Serbanovic-Canic, J., Stemple, D.L., and Ouwehand, W.H. (2011) The Role Of Meis1 In Primitive And Definitive Hematopoiesis During Zebrafish Development. Haematologica. 96(2):190-198
Clark, M.D., Guryev, V., Bruijn, E., Nijman, I.J., Tada, M., Wilson, C., Deloukas, P., Postlethwait, J.H., Cuppen, E., and Stemple, D.L. (2011) Single nucleotide polymorphism (SNP) panels for rapid positional cloning in zebrafish. Methods in cell biology. 104:219-235
Zheng, W., Wang, Z., Collins, J.E., Andrews, R.M., Stemple, D., and Gong, Z. (2011) Comparative transcriptome analyses indicate molecular homology of zebrafish swimbladder and Mammalian lung. PLoS One. 6(8):e24019
Kettleborough, R.N., Bruijn, E., Eeden, F., Cuppen, E., and Stemple, D.L. (2011) High-throughput target-selected gene inactivation in zebrafish. Methods in cell biology. 104:121-127
Busch-Nentwich, E., Kettleborough, R., Fenyes, F., Herd, C., Collins, J., de Bruijn, E., van Eeden, F., Cuppen, E., and Stemple, D.L. (2010) Sanger Institute Zebrafish Mutation Resource targeted knock-out mutants phenotype and image data submission, Sanger Institute Zebrafish Mutation Resource and Hubrecht laboratory. ZFIN Direct Data Submission.
Busch-Nentwich, E., Kettleborough, R., Fenyes, F., Herd, C., Collins, J., and Stemple, D.L. (2010) Sanger Institute Zebrafish Mutation Resource targeted knock-out mutants phenotype and image data submission. ZFIN Direct Data Submission.
Busch-Nentwich, E., Kettleborough, R., Fenyes, F., Herd, C., Collins, J., Winkler, S., Brand, M., de Bruijn, E., van Eeden, F., Cuppen, E., and Stemple, D.L. (2010) Sanger Institute Zebrafish Mutation Resource targeted knock-out mutants phenotype and image data submission, Sanger Institute Zebrafish Mutation Resource, MPI Dresden, and Hubrecht laboratory. ZFIN Direct Data Submission.
Jacoby, A.S., Busch-Nentwich, E., Bryson-Richardson, R.J., Hall, T.E., Berger, J., Berger, S., Sonntag, C., Sachs, C., Geisler, R., Stemple, D.L., and Currie, P.D. (2009) The zebrafish dystrophic mutant softy maintains muscle fibre viability despite basement membrane rupture and muscle detachment. Development (Cambridge, England). 136(19):3367-3376
O'Connor, M.N., Salles, I.I., Cvejic, A., Watkins, N.A., Walker, A., Garner, S.F., Jones, C.I., Macaulay, I.C., Steward, M., Zwaginga, J.J., Bray, S.L., Dudbridge, F., de Bono, B., Goodall, A.H., Deckmyn, H., Stemple, D.L., and Ouwehand, W.H. (2009) Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins. Blood. 113(19):4754-4762
Ferrante, M.I., Romio, L., Castro, S., Collins, J.E., Goulding, D.A., Stemple, D.L., Woolf, A.S., and Wilson, S.W. (2009) Convergent Extension Movements and Ciliary Function are Mediated by ofd1, A Zebrafish Orthologue of the Human Oral-Facial-Digital Type 1 Syndrome Gene. Human molecular genetics. 18(2):289-303
Noël, E.S., Casal-Sueiro, A., Busch-Nentwich, E., Verkade, H., Dong, P.D., Stemple, D.L., and Ober, E.A. (2008) Organ-specific requirements for Hdac1 in liver and pancreas formation. Developmental Biology. 322(2):237-250
Xu, Q., Stemple, D., and Joubin, K. (2008) Microinjection and cell transplantation in zebrafish embryos. Methods in molecular biology (Clifton, N.J.). 461:513-520
Pei, W., Williams, P.H., Clark, M.D., Stemple, D.L., and Feldman, B. (2007) Environmental and genetic modifiers of squint penetrance during zebrafish embryogenesis. Developmental Biology. 308(2):368-378
Ekker, S.C., Stemple, D.L., Clark, M., Chien, C.B., Rasooly, R.S., and Javois, L.C. (2007) Zebrafish genome project: bringing new biology to the vertebrate genome field. Zebrafish. 4(4):239-251
Pollard, S.M., Parsons, M.J., Kamei, M., Kettleborough, R.N., Thomas, K.A., Pham, V.N., Bae, M.K., Scott, A., Weinstein, B.M., and Stemple, D.L. (2006) Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation. Developmental Biology. 289(1):64-76
Scott, A., and Stemple, D. (2005) Zebrafish notochordal basement membrane: signaling and structure. Current topics in developmental biology. 65:229-253
Thomas, K.A., and Stemple, D.L. (2004) Development of the Zebrafish Organiser and Notochord. In Fish Development and Genetics - the Zebrafish and Medaka Models. Gong, Z. and Korh, V., Eds. Book series of "Molecular Aspects of Fish and Marine Biology". 2
Coutinho, P., Parsons, M.J., Thomas, K.A., Hirst, E.M., Saude, L., Campos, I., Williams, P.H., Stemple, D.L. (2004) Differential Requirements for COPI Transport during Vertebrate Early Development. Developmental Cell. 7(4):547-558
Zhang, C., Basta, T., Hernandez-Lagunas, L., Simpson, P., Stemple, D.L., Artinger, K.B., and Klymkowsky, M.W. (2004) Repression of nodal expression by maternal B1-type SOXs regulates germ layer formation in Xenopus and zebrafish. Developmental Biology. 273(1):23-37
Feldman, B., Concha, M.L., Saude, L., Parsons, M.J., Adams, R.J., Wilson, S.W., and Stemple, D.L. (2002) Lefty antagonism of squint is essential for normal gastrulation. Current biology : CB. 12(24):2129-2135
Parsons, M.J., Campos, I., Hirst, E.M.A., and Stemple, D.L. (2002) Removal of dystroglycan causes severe muscular dystrophy in zebrafish embryos. Development (Cambridge, England). 129(14):3505-3512
Parsons, M.J., Pollard, S.M., Saude, L., Feldman, B., Coutinho, P., Hirst, E.M., and Stemple, D.L. (2002) Zebrafish mutants identify an essential role for laminins in notochord formation. Development (Cambridge, England). 129(13):3137-3146
Stemple, D.L. (2002) Pioneering work in vertebrate neural development. Developmental Cell. 2(6):687-688
Feldman, B. and Stemple, D.L. (2001) Morpholino phenocopies of sqt, oep, and ntl mutations. Genesis (New York, N.Y. : 2000). 30(3):175-177
Heisenberg, C.P., Houart, C., Take-uchi, M., Rauch, G.J., Young, N., Coutinho, P., Masai, I., Caneparo, L., Concha, M.L., Geisler, R., Dale, T.C., Wilson, S.W., and Stemple, D.L. (2001) A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes & Development. 15(11):1427-1434
Stemple, D.L. (2000) Vertebrate development: The fast track to Nodal signalling. Current biology : CB. 10(22):R843-R846
Saude, L., Woolley, K., Martin, P., Driever, W., and Stemple, D.L. (2000) Axis-inducing activities and cell fates of the zebrafish organizer. Development (Cambridge, England). 127(16):3407-3417
Masai, I., Stemple, D.L., Okamoto, H., and Wilson, S.W. (2000) Midline signals regulate retinal neurogenesis in zebrafish. Neuron. 27(2):251-263
Heisenberg, C.P., Tada, M., Rauch, G.J., Saude, L., Concha, M.L., Geisler, R., Stemple, D.L., Smith, J.C., and Wilson, S.W. (2000) Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. Nature. 405(6782):76-81
Fekany, K., Yamanaka, Y., Leung, T., Sirotkin, H.I., Topczewski, J., Gates, M.A., Hibi, M., Renucci, A., Stemple, D., Radbill, A., Schier, A.F., Driever, W., Hirano, T., Talbot, W.S., and Solnica-Krezel, L. (1999) The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures. Development (Cambridge, England). 126:1427-1438
Drummond, I.A., Majumdar, A., Hentschel, H., Elger, M., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Stemple, D.L., Zwartkruis, F., Rangini, Z., Driever, W., and Fishman, M.C. (1998) Early development of the zebrafish pronephros and analysis of mutations affecting pronephric function. Development (Cambridge, England). 125:4655-4667
Driever, W., Solnica-Krezel, L., Abdelilah, S., Meyer, D., and Stemple, D. (1997) Genetic analysis of pattern formation in the zebrafish neural plate. Cold Spring Harbor symposia on quantitative biology. 62:523-534
Stemple, D.L. and Driever, W. (1996) Zebrafish: Tools for investigating cellular differentiation. Current opinion in cell biology. 8(6):858-864
Pack, M., Solnica-Krezel, L., Malicki, J., Neuhauss, S.C., Schier, A-, F., Stemple, D.L., Driever, W., and Fishman, M.C. (1996) Mutations affecting development of zebrafish digestive organs. Development (Cambridge, England). 123:321-328
Driever, W., Solnica-Krezel, L., Schier, A.F., Neuhauss, S.C., Malicki, J., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Rangini, Z., Belak, J., and Boggs, C. (1996) A genetic screen for mutations affecting embryogenesis in zebrafish. Development (Cambridge, England). 123:37-46
Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Abdelilah, S., Stainier, D.Y., and Driever, W. (1996) Mutations affecting craniofacial development in zebrafish. Development (Cambridge, England). 123:357-367
Solnica-Krezel, L., Stemple, D.L., Mountcastle-Shah, E., Rangini, Z., Neuhauss, S.C., Malicki, J., Schier, A.F., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., and Driever, W. (1996) Mutations affecting cell fates and cellular rearrangements during gastrulation in zebrafish. Development (Cambridge, England). 123:67-80
Stemple, D.L., Solnica-Krezel, L., Zwartkruis, F., Neuhauss, S.C., Schier, A.F., Malicki, J., Stainier, D.Y., Abdelilah, S., Rangini, Z., Mountcastle-Shah, E., and Driever, W. (1996) Mutations affecting development of the notochord in zebrafish. Development (Cambridge, England). 123:117-128
Schier, A.F., Neuhauss, S.C., Harvey, M., Malicki, J., Solnica-Krezel, L., Stainier, D.Y., Zwartkruis, F., Abdelilah, S., Stemple, D.L., Rangini, Z., Yang, H., and Driever, W. (1996) Mutations affecting the development of the embryonic zebrafish brain. Development (Cambridge, England). 123:165-178
Abdelilah, S., Mountcastle-Shah, E., Harvey, M., Solnica-Krezel, L., Schier, A.F., Stemple, D.L., Malicki, J., Neuhauss, S.C., Zwartkruis, F., Stainier, D.Y., Rangini, Z., and Driever, W. (1996) Mutations affecting neural survival in the zebrafish Danio rerio. Development (Cambridge, England). 123:217-227
Malicki, J., Neuhauss, S.C., Schier, A.F., Solnica-Krezel, L., Stemple, D.L., Stainier, D.Y., Abdelilah, S., Zwartkruis, F., Rangini, Z., and Driever, W. (1996) Mutations affecting development of the zebrafish retina. Development (Cambridge, England). 123:263-273
Malicki, J., Schier, A.F., Solnica-Krezel, L., Stemple, D.L., Neuhauss, S.C., Stainier, D.Y., Abdelilah, S., Rangini, Z., Zwartkruis, F., and Driever, W. (1996) Mutations affecting development of the zebrafish ear. Development (Cambridge, England). 123:275-283
Stainier, D.Y., Fouquet, B., Chen, J.N., Warren, K.S., Weinstein, B.M., Meiler, S.E., Mohideen, M.A., Neuhauss, S.C., Solnica-Krezel, L., Schier, A.F., Zwartkruis, F., Stemple, D.L., Malicki, J., Driever, W., and Fishman, M.C. (1996) Mutations affecting the formation and function of the cardiovascular system in the zebrafish embryo. Development (Cambridge, England). 123:285-292
Weinstein, B.M., Schier, A.F., Abdelilah, S., Malicki, J., Solnica-Krezel, L., Stemple, D.L., Stainier, D.Y., Zwartkruis, F., Driever, W., and Fishman, M.C. (1996) Hematopoietic mutations in the zebrafish. Development (Cambridge, England). 123:303-309
Abdelilah, S.,Driever, W., Gorn, A., Malicki,J., Neuhauss, S., Pack, M., Rangini, Z., Schier, A., Solnica-Krezel, L., Stanier, D., and Stemple, D. (1996) Anatomy of the 24, 48, 72 and 120 hours Zebrafish (Danio rerio) Embryo. ZFIN Direct Data Submission.
Weinstein, B.M., Stemple, D.L., Driever, W., and Fishman, M.C. (1995) Gridlock, a localized heritable vascular patterning defect in the zebrafish. Nature medicine. 1(11):1143-1147
Solnica-Krezel, L., Stemple, D.L., and Driever, W. (1995) Transparent things: cell fates and cell movements during early embryogenesis of zebrafish. BioEssays : news and reviews in molecular, cellular and developmental biology. 17:931-939
Driever, W., Stemple, D., Schier, A., and Solnica-Krezel, L. (1994) Zebrafish: genetic tools for studying vertebrate development. Trends in genetics : TIG. 10:152-159