Morpholino

MO2-spen

ID

ZDB-MRPHLNO-220307-2

Name

MO2-spen

Previous Names

None

Target

Sequence

5' - CTCAGCAAATCGTCACTTACCGTTT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

Splice blocker MO for exon 1/intron 1.

Genome Resources

None

Target Location

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-spen

Expressed Gene	Anatomy	Figures
gja1b	heart	Fig. 4 from Rattka et al., 2021

Phenotype

Phenotype resulting from MO2-spen

Phenotype	Fish	Figures
AV node cell action potential disrupted, abnormal	AB/TU + MO2-spen	Fig. 3 from Rattka et al., 2021
cardiac ventricle decreased contractility, abnormal	AB/TU + MO2-spen	Fig. 2 from Rattka et al., 2021
heart gja1b expression decreased amount, abnormal	AB/TU + MO2-spen	Fig. 4 from Rattka et al., 2021
heart decreased functionality, abnormal	AB/TU + MO2-spen	Fig. 2 , Fig. 3 from Rattka et al., 2021
heart contraction decreased rate, abnormal	AB/TU + MO2-spen	Fig. 1 , Fig. 2 from Rattka et al., 2021
heart contraction disrupted, abnormal	AB/TU + MO2-spen	Fig. 1 from Rattka et al., 2021
pericardium edematous, abnormal	AB/TU + MO2-spen	Fig. 1 from Rattka et al., 2021

Phenotype of all Fish created by or utilizing MO2-spen

Phenotype	Fish	Conditions	Figures
heart gja1b expression decreased amount, abnormal	AB/TU + MO2-spen	standard conditions	Fig. 4 from Rattka et al., 2021
cardiac ventricle decreased contractility, abnormal	AB/TU + MO2-spen	standard conditions	Fig. 2 from Rattka et al., 2021
heart contraction disrupted, abnormal	AB/TU + MO2-spen	standard conditions	Fig. 1 from Rattka et al., 2021
heart contraction decreased rate, abnormal	AB/TU + MO2-spen	standard conditions	Fig. 1 , Fig. 2 from Rattka et al., 2021
pericardium edematous, abnormal	AB/TU + MO2-spen	standard conditions	Fig. 1 from Rattka et al., 2021
heart decreased functionality, abnormal	AB/TU + MO2-spen	standard conditions	Fig. 2 , Fig. 3 from Rattka et al., 2021
AV node cell action potential disrupted, abnormal	AB/TU + MO2-spen	standard conditions	Fig. 3 from Rattka et al., 2021
heart decreased functionality, abnormal	AB/TU + MO2-spen + MO6-gja1b	standard conditions	Fig. 7 from Rattka et al., 2021
pericardium edematous, abnormal	AB/TU + MO2-spen + MO6-gja1b	standard conditions	Fig. 7 from Rattka et al., 2021

Citations