ZFIN Morpholino: MO2-gata5

Target Location

Genome Build: GRCz11Chromosome: 23

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO2-gata5

No data available

Phenotype

Phenotype resulting from MO2-gata5

Phenotype	Fish	Figures
heart bifurcated, abnormal	WT + MO2-gata5	Fig. 1 from Holtzinger et al., 2007
heart decreased size, abnormal	twu34Tg + MO2-gata5	Fig. S4 from Gupta et al., 2013
heart physical object quality, abnormal	WT + MO2-gata5	Fig. 1 from Holtzinger et al., 2007
heart looping disrupted, abnormal	AB + MO2-gata5	Fig. 4 from Li et al., 2011
heart morphogenesis decreased process quality, abnormal	twu34Tg + MO2-gata5	Fig. S4 from Gupta et al., 2013

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Phenotype of all Fish created by or utilizing MO2-gata5

Phenotype	Fish	Conditions	Figures
heart looping disrupted, abnormal	AB + MO2-gata5	standard conditions	Fig. 4 from Li et al., 2011
left/right pattern formation disrupted, abnormal	AB + MO2-gata5	standard conditions	Fig. 4 from Li et al., 2011
heart bifurcated, abnormal	WT + MO2-gata5	standard conditions	Fig. 1 from Holtzinger et al., 2007
heart physical object quality, abnormal	WT + MO2-gata5	standard conditions	Fig. 1 from Holtzinger et al., 2007
heart morphogenesis decreased process quality, abnormal	twu34Tg + MO2-gata5	standard conditions	Fig. S4 from Gupta et al., 2013

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Citations

Include unpublished citations

Wen, B., Yuan, H., Liu, X., Wang, H., Chen, S., Chen, Z., de The, H., Zhou, J., Zhu, J. (2017) GATA5 SUMOylation is indispensable for zebrafish cardiac development. Biochimica et biophysica acta. 1861(7):1691-1701
Gupta, V., Gemberling, M., Karra, R., Rosenfeld, G.E., Evans, T., and Poss, K.D. (2013) An Injury-Responsive Gata4 Program Shapes the Zebrafish Cardiac Ventricle. Current biology : CB. 23(13):1221-7
Novikov, N., and Evans, T. (2013) Tmem88a mediates GATA-dependent specification of cardiomyocyte progenitors by restricting WNT signaling. Development (Cambridge, England). 140(18):3787-98
Torregroza, I., Holtzinger, A., Mendelson, K., Liu, T.C., Hla, T., and Evans, T. (2012) Regulation of a Vascular Plexus by gata4 Is Mediated in Zebrafish through the Chemokine sdf1a. PLoS One. 7(10):e46844
Li, N., Wei, C., Olena, A.F., and Patton, J.G. (2011) Regulation of endoderm formation and left-right asymmetry by miR-92 during early zebrafish development. Development (Cambridge, England). 138(9):1817-1826
Holtzinger, A., and Evans, T. (2007) Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytes. Developmental Biology. 312(2):613-622

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