ZFIN is now using GRCz12tu for Genomic Data
Gene
gata5
- ID
- ZDB-GENE-980526-340
- Name
- GATA binding protein 5
- Symbol
- gata5 Nomenclature History
- Previous Names
-
- gta5
- cb634 (1)
- fau
- faust
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of with a negative effect on gene expression. Acts upstream of or within several processes, including Kupffer's vesicle development; heart development; and post-embryonic foregut morphogenesis. Located in nucleus. Is expressed in several structures, including blastoderm; cardiovascular system; digestive system; mesoderm; and presumptive structure. Human ortholog(s) of this gene implicated in artery disease (multiple); atrial fibrillation (multiple); congenital heart disease (multiple); and dilated cardiomyopathy. Orthologous to human GATA5 (GATA binding protein 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 93 figures from 69 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb634 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 24 figures from 15 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Congenital heart defects, multiple types, 5 | 617912 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | GATA-type transcription activator, N-terminal | Transcription factor GATA | Transcription factor GATA-4/5/6 | Zinc finger, GATA-type | Zinc finger, NHR/GATA-type |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q9W6U0 | InterPro | 383 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers