ZFIN Morpholino: MO1-crkl

Target Location

Genome Build: GRCz11Chromosome: 21

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-crkl

No data available

Phenotype

Phenotype resulting from MO1-crkl

Phenotype	Fish	Figures
fast muscle cell circular, abnormal	WT + MO1-crkl	Fig. 3 from Moore et al., 2007
fast muscle cell mononucleate, abnormal	WT + MO1-crkl	Fig. 3 , Fig. 4 from Moore et al., 2007
myoblast fusion decreased occurrence, abnormal	WT + MO1-crkl	Fig. 3 , Fig. 4 from Moore et al., 2007
pronephric proximal convoluted tubule morphology, abnormal	zf34Tg + MO1-crkl	Fig. 2 from Lopez-Rivera et al., 2017
pronephros decreased length, abnormal	zf34Tg + MO1-crkl	Fig. 2 from Lopez-Rivera et al., 2017

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Phenotype of all Fish created by or utilizing MO1-crkl

Phenotype	Fish	Conditions	Figures
myoblast fusion decreased occurrence, abnormal	WT + MO1-crkl	standard conditions	Fig. 3 , Fig. 4 from Moore et al., 2007
fast muscle cell circular, abnormal	WT + MO1-crkl	standard conditions	Fig. 3 from Moore et al., 2007
fast muscle cell mononucleate, abnormal	WT + MO1-crkl	standard conditions	Fig. 3 , Fig. 4 from Moore et al., 2007
pronephric proximal convoluted tubule morphology, abnormal	zf34Tg + MO1-crkl	standard conditions	Fig. 2 from Lopez-Rivera et al., 2017
pronephros decreased length, abnormal	zf34Tg + MO1-crkl	standard conditions	Fig. 2 from Lopez-Rivera et al., 2017

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Citations

Include unpublished citations

Lopez-Rivera, E., Liu, Y.P., Verbitsky, M., Anderson, B.R., Capone, V.P., Otto, E.A., Yan, Z., Mitrotti, A., Martino, J., Steers, N.J., Fasel, D.A., Vukojevic, K., Deng, R., Racedo, S.E., Liu, Q., Werth, M., Westland, R., Vivante, A., Makar, G.S., Bodria, M., Sampson, M.G., Gillies, C.E., Vega-Warner, V., Maiorana, M., Petrey, D.S., Honig, B., Lozanovski, V.J., Salomon, R., Heidet, L., Carpentier, W., Gaillard, D., Carrea, A., Gesualdo, L., Cusi, D., Izzi, C., Scolari, F., van Wijk, J.A., Arapovic, A., Saraga-Babic, M., Saraga, M., Kunac, N., Samii, A., McDonald-McGinn, D.M., Crowley, T.B., Zackai, E.H., Drozdz, D., Miklaszewska, M., Tkaczyk, M., Sikora, P., Szczepanska, M., Mizerska-Wasiak, M., Krzemien, G., Szmigielska, A., Zaniew, M., Darlow, J.M., Puri, P., Barton, D., Casolari, E., Furth, S.L., Warady, B.A., Gucev, Z., Hakonarson, H., Flogelova, H., Tasic, V., Latos-Bielenska, A., Materna-Kiryluk, A., Allegri, L., Wong, C.S., Drummond, I.A., D'Agati, V., Imamoto, A., Barasch, J.M., Hildebrandt, F., Kiryluk, K., Lifton, R.P., Morrow, B.E., Jeanpierre, C., Papaioannou, V.E., Ghiggeri, G.M., Gharavi, A.G., Katsanis, N., Sanna-Cherchi, S. (2017) Genetic Drivers of Kidney Defects in the DiGeorge Syndrome. The New England Journal of Medicine. 376(8):742-754
Moore, C.A., Parkin, C.A., Bidet, Y., and Ingham, P.W. (2007) A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion. Development (Cambridge, England). 134(17):3145-3153

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