ZFIN Morpholino: MO1-mespba

Target Location

Genome Build: GRCz11Chromosome: 7

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-mespba

No data available

Phenotype

Phenotype resulting from MO1-mespba

Phenotype	Fish	Figures
determination of heart left/right asymmetry decreased efficacy, abnormal	WT + MO1-mespba	Fig. 4 from Deshwar et al., 2016
heart primordium lft2 expression absent, abnormal	WT + MO1-mespba	Fig. 4 from Deshwar et al., 2016
heart primordium lft1 expression absent, abnormal	WT + MO1-mespba	Fig. 4 from Deshwar et al., 2016
left/right pattern formation decreased efficacy, abnormal	WT + MO1-mespba	Fig. 4 from Deshwar et al., 2016

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Phenotype of all Fish created by or utilizing MO1-mespba

Phenotype	Fish	Conditions	Figures
somitogenesis disrupted, abnormal	TL + MO1-mespba	cold exposure	Fig. 2, Fig. S1 from Kawamura et al., 2005
heart primordium lft1 expression absent, abnormal	WT + MO1-mespba	standard conditions	Fig. 4 from Deshwar et al., 2016
determination of heart left/right asymmetry decreased efficacy, abnormal	WT + MO1-mespba	standard conditions	Fig. 4 from Deshwar et al., 2016
heart primordium lft2 expression absent, abnormal	WT + MO1-mespba	standard conditions	Fig. 4 from Deshwar et al., 2016
left/right pattern formation decreased efficacy, abnormal	WT + MO1-mespba	standard conditions	Fig. 4 from Deshwar et al., 2016

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Citations

Include unpublished citations

Deshwar, A.R., Onderisin, J.C., Aleksandrova, A., Yuan, X., Burrows, J.T., Scott, I.C. (2016) Mespaa can potently induce cardiac fates in zebrafish. Developmental Biology. 418(1):17-27
Windner, S.E., Doris, R.A., Ferguson, C.M., Nelson, A.C., Valentin, G., Tan, H., Oates, A.C., Wardle, F.C., Devoto, S.H. (2015) Tbx6, Mesp-b and Ripply1 regulate the onset of skeletal myogenesis in zebrafish. Development (Cambridge, England). 142(6):1159-68
Akiyama, R., Masuda, M., Tsuge, S., Bessho, Y., and Matsui, T. (2014) An anterior limit of FGF/Erk signal activity marks the earliest future somite boundary in zebrafish. Development (Cambridge, England). 141(5):1104-1109
Lee, H.C., Tseng, W.A., Lo, F.Y., Liu, T.M., and Tsai, H.J. (2009) FoxD5 mediates anterior-posterior polarity through upstream modulator Fgf signaling during zebrafish somitogenesis. Developmental Biology. 336(2):232-245
Kawamura, A., Koshida, S., Hijikata, H., Ohbayashi, A., Kondoh, H., and Takada, S. (2005) Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites. Developmental Cell. 9(6):735-744

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