ZFIN Morpholino: MO1-notch1a

Target Location

Genome Build: GRCz11Chromosome: 21

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-notch1a

No data available

Phenotype

Phenotype resulting from MO1-notch1a

Phenotype	Fish	Figures
choroid plexus fourth ventricle shape, abnormal	mn16Et + MO1-notch1a	Fig. 5 from Bill et al., 2008

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Phenotype of all Fish created by or utilizing MO1-notch1a

Phenotype	Fish	Conditions	Figures
choroid plexus fourth ventricle shape, abnormal	mn16Et + MO1-notch1a	standard conditions	Fig. 5 from Bill et al., 2008
whole organism runx1 expression amount, ameliorated	TU + MO1-mettl3 + MO1-notch1a	standard conditions	Fig. 3 from Zhang et al., 2017
retinal cone cell amount, ameliorated	WT + MO1-id2a + MO1-notch1a	control	Fig. 5 from Uribe et al., 2012
retina cell population proliferation process quality, ameliorated	WT + MO1-id2a + MO1-notch1a	standard conditions	Fig. 4 from Uribe et al., 2012
eye cell amount, ameliorated	WT + MO1-id2a + MO1-notch1a	standard conditions	Fig. 4 from Uribe et al., 2012

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Citations

Include unpublished citations

Campbell, L.J., Hobgood, J.S., Jia, M., Boyd, P., Hipp, R.I., Hyde, D.R. (2020) Notch3 and DeltaB maintain Müller glia quiescence and act as negative regulators of regeneration in the light-damaged zebrafish retina. Glia. 69(3):546-566
Zhang, C., Chen, Y., Sun, B., Wang, L., Yang, Y., Ma, D., Lv, J., Heng, J., Ding, Y., Xue, Y., Lu, X., Xiao, W., Yang, Y.G., Liu, F. (2017) m⁶A modulates haematopoietic stem and progenitor cell specification.. Nature. 549(7671):273-276
Bainbridge, M.N., Davis, E.E., Choi, W.Y., Dickson, A., Martinez, H.R., Wang, M., Dinh, H., Muzny, D., Pignatelli, R., Katsanis, N., Boerwinkle, E., Gibbs, R., Jefferies, J.L. (2015) Loss of Function Mutations in NNT Are Associated with Left Ventricular Noncompaction. Circulation. Cardiovascular genetics. 8(4):544-52
Kressmann, S., Campos, C., Castanon, I., Fürthauer, M., González-Gaitán, M. (2015) Directional Notch trafficking in Sara endosomes during asymmetric cell division in the spinal cord. Nature cell biology. 17(3):333-9
Da'as, S.I., Coombs, A.J., Balci, T.B., Grondin, C.A., Ferrando, A.A., and Berman, J.N. (2012) The zebrafish reveals dependence of the mast cell lineage on Notch signaling in vivo. Blood. 119(15):3585-3594
Uribe, R.A., Kwon, T., Marcotte, E.M., and Gross, J.M. (2012) Id2a functions to limit Notch pathway activity and thereby influence the transition from proliferation to differentiation of retinoblasts during zebrafish retinogenesis. Developmental Biology. 371(2):280-292
Ishitani, T., Hirao, T., Suzuki, M., Isoda, M., Ishitani, S., Harigaya, K., Kitagawa, M., Matsumoto, K., and Itoh, M. (2010) Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex. Nature cell biology. 12(3):278-285
Matsuda, M., and Chitnis, A.B. (2010) Atoh1a expression must be restricted by Notch signaling for effective morphogenesis of the posterior lateral line primordium in zebrafish. Development (Cambridge, England). 137(20):3477-3487
Matsuda, M., and Chitnis, A.B. (2009) Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue. Development (Cambridge, England). 136(2):197-206
So, J.H., Chun, H.S., Bae, Y.K., Kim, H.S., Park, Y.M., Huh, T.L., Chitnis, A.B., Kim, C.H., and Yeo, S.Y. (2009) Her4 is necessary for establishing peripheral projections of the trigeminal ganglia in zebrafish. Biochemical and Biophysical Research Communications. 379(1):22-26

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