ZFIN Lab: Ceol Lab

ZFIN ID: ZDB-LAB-160811-1

Ceol Lab

PI/Director:	Ceol, Craig
Contact Person:	Ceol, Craig
Email:	Craig.Ceol@umassmed.edu
URL:	https://pmm.umassmed.edu/Ceol/index.html
Address:	University of Massachusetts Medical School Albert Sherman Center AS6-1041 368 Plantation Street Worcester, MA 01605
Country:	United States
Phone:	508-856-5509
Fax:
Line Designation:	um

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 5 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

Frantz, W.T., Iyengar, S., Neiswender, J., Cousineau, A., Maehr, R., Ceol, C.J. (2023) Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish. eLIFE. 12:

Darp, R., Vittoria, M.A., Ganem, N.J., Ceol, C.J. (2022) Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis. Nature communications. 13:4109

Wilcock, D.J., Badrock, A.P., Wong, C.W., Owen, R., Guerin, M., Southam, A.D., Johnston, H., Telfer, B.A., Fullwood, P., Watson, J., Ferguson, H., Ferguson, J., Lloyd, G.R., Jankevics, A., Dunn, W.B., Wellbrock, C., Lorigan, P., Ceol, C., Francavilla, C., Smith, M.P., Hurlstone, A.F.L. (2022) Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached. Cell Reports. 39:110995

Frantz, W.T., Ceol, C.J. (2022) Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease. The Journal of investigative dermatology. 142:499-506.e1

Patton, E.E., Mueller, K.L., Adams, D.J., Anandasabapathy, N., Aplin, A.E., Bertolotto, C., Bosenberg, M., Ceol, C.J., Chi, P., Herlyn, M., Holmen, S.L., Karreth, F.A., Kaufman, C.K., Khan, S., Kobold, S., Leucci, E., Levy, C., Lombard, D.B., Lund, A.W., Marie, K.L., Marine, J.C., Marais, R., McMahon, M., Robles-Espinoza, C.D., Ronai, Z.A., Samuels, Y., Soengas, M.S., Villanueva, J., Weeraratna, A.T., White, R.M., Yeh, I., Zhu, J., Zon, L.I., Hurlbert, M.S., Merlino, G. (2021) Melanoma models for the next generation of therapies. Cancer Cell. 39(5):610-631

Iwanaga, R., Truong, B.T., Hsu, J.Y., Lambert, K.A., Vyas, R., Orlicky, D., Shellman, Y.G., Tan, A.C., Ceol, C., Artinger, K.B. (2020) Loss of prdm1a accelerates melanoma onset and progression. Molecular Carcinogenesis. 59(9):1052-1063

Frantz, W.T., Ceol, C.J. (2020) From Tank to Treatment: Modeling Melanoma in Zebrafish. Cells. 9(5):

Gramann, A.K., Venkatesan, A.M., Guerin, M., Ceol, C.J. (2019) Regulation of zebrafish melanocyte development by ligand-dependent BMP signaling. eLIFE. 8:

Venkatesan, A.M., Vyas, R., Gramann, A.K., Dresser, K., Gujja, S., Bhatnagar, S., Chhangawala, S., Gomes, C.B.F., Xi, H.S., Lian, C.G., Houvras, Y., Edwards, Y.J.K., Deng, A., Green, M., Ceol, C.J. (2017) Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. The Journal of Clinical Investigation. 128(1):294-308

Neiswender, J.V., Kortum, R.L., Bourque, C., Kasheta, M., Zon, L., Morrison, D.K., Ceol, C.J. (2017) KIT Suppresses BRAF^V600E-Mutant Melanoma by Attenuating Oncogenic RAS/MAPK Signaling.. Cancer research. 77(21):5820-5830

Kasheta, M., Painter, C.A., Moore, F.E., Lobbardi, R., Bryll, A., Freiman, E., Stachura, D., Rogers, A.B., Houvras, Y., Langenau, D.M., Ceol, C.J. (2017) Identification and characterization of T reg-like cells in zebrafish. The Journal of experimental medicine. 214(12):3519-3530

Tang, Q., Iyer, S., Lobbardi, R., Moore, J.C., Chen, H., Lareau, C., Hebert, C., Shaw, M.L., Neftel, C., Suva, M.L., Ceol, C.J., Bernards, A., Aryee, M., Pinello, L., Drummond, I.A., Langenau, D.M. (2017) Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing. The Journal of experimental medicine. 214(10):2875-2887

Neto, A., Ceol, C.J. (2017) Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling. Pigment cell & melanoma research. 31(1):115-119

Moore, F.E., Garcia, E.G., Lobbardi, R., Jain, E., Tang, Q., Moore, J.C., Cortes, M., Molodtsov, A., Kasheta, M., Luo, C.C., Garcia, A.J., Mylvaganam, R., Yoder, J.A., Blackburn, J.S., Sadreyev, R.I., Ceol, C.J., North, T.E., Langenau, D.M. (2016) Single-cell transcriptional analysis of normal, aberrant, and malignant hematopoiesis in zebrafish. The Journal of experimental medicine. 213(6):979-92

Ceol, C.J., Houvras, Y. (2016) Uncharted Waters: Zebrafish Cancer Models Navigate a Course for Oncogene Discovery. Advances in experimental medicine and biology. 916:3-19

Wojciechowska, S., van Rooijen, E., Ceol, C., Patton, E.E., White, R.M. (2016) Generation and analysis of zebrafish melanoma models. Methods in cell biology. 134:531-49

Wojciechowska, S., Zeng, Z., Lister, J.A., Ceol, C.J., Patton, E.E. (2016) Melanoma Regression and Recurrence in Zebrafish. Methods in molecular biology (Clifton, N.J.). 1451:143-53

Iyengar, S., Kasheta, M., Ceol, C.J. (2015) Poised Regeneration of Zebrafish Melanocytes Involves Direct Differentiation and Concurrent Replenishment of Tissue-Resident Progenitor Cells. Developmental Cell. 33(6):631-43

Painter, C.A., Ceol, C.J. (2014) Zebrafish as a platform to study tumor progression. Methods in molecular biology (Clifton, N.J.). 1176:143-55

Iyengar, S., Houvras, Y., and Ceol, C.J. (2012) Screening for Melanoma Modifiers using a Zebrafish Autochthonous Tumor Model. Journal of visualized experiments : JoVE. (69):e50086

Richardson, J., Zeng, Z., Ceol, C., Mione, M., Jackson, I.J., and Patton, E.E. (2011) A zebrafish model for nevus regeneration. Pigment cell & melanoma research. 24(2):378-381

Ceol, C.J., Houvras, Y., Jane-Valbuena, J., Bilodeau, S., Orlando, D.A., Battisti, V., Fritsch, L., Lin, W.M., Hollmann, T.J., Ferré, F., Bourque, C., Burke, C.J., Turner, L., Uong, A., Johnson, L.A., Beroukhim, R., Mermel, C.H., Loda, M., Ait-Si-Ali, S., Garraway, L.A., Young, R.A., and Zon, L.I. (2011) The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature. 471(7339):513-517

North, T.E., Goessling, W., Peeters, M., Li, P., Ceol, C., Lord, A.M., Weber, G.J., Harris, J., Cutting, C.C., Huang, P., Dzierzak, E., and Zon, L.I. (2009) Hematopoietic stem cell development is dependent on blood flow. Cell. 137(4):736-748

Freeman, J.L., Ceol, C., Feng, H., Langenau, D.M., Belair, C., Stern, H.M., Song, A., Paw, B.H., Look, A.T., Zhou, Y., Zon, L.I., and Lee, C. (2009) Construction and application of a zebrafish array comparative genomic hybridization platform. Genes, chromosomes & cancer. 48(2):155-170

Ceol, C.J., Houvras, Y., White, R.M., and Zon, L.I. (2008) Melanoma biology and the promise of zebrafish. Zebrafish. 5(4):247-255

Goessling, W., North, T.E., Lord, A.M., Ceol, C., Lee, S., Weidinger, G., Bourque, C., Strijbosch, R., Haramis, A.P., Puder, M., Clevers, H., Moon, R.T., and Zon, L.I. (2008) APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Developmental Biology. 320(1):161-174

Langenau, D.M., Keefe, M.D., Storer, N.Y., Jette, C.A., Smith, A.C., Ceol, C.J., Bourque, C., Look, A.T., and Zon, L.I. (2008) Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish. Oncogene. 27(30):4242-4248

White, R.M., Sessa, A., Burke, C., Bowman, T., LeBlanc, J., Ceol, C. Bourque, C., Dovey, M., Goessling, W., Burns, C.E., and Zon, L.I. (2008) Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis. Cell Stem Cell. 2(2):183-189