ZFIN ID: ZDB-LAB-121108-1
Cell Biology of Neural Development
PI/Director: Zolessi, Flavio
Contact Person: Zolessi, Flavio
Email: fzolessi@fcien.edu.uy
Address: Institut Pasteur de Montevideo Mataojo 2020 Montevideo, 11400 Uruguay AND Seccion Biologia Celular, Facultad de Ciencias, Universidad de la Republica Igua 4225 Montevideo, 11400 Uruguay
Country: Uruguay
Phone: +598 2522 0910
Fax: +598 2525 8629
Line Designation: ipm

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Our general research interest is centered on understanding the mechanisms of neural differentiation, both in normal and pathological situations. In particular, the main focus is on understanding cell polarity transitions that occur through the different stages of neural development in vertebrates, from neurulation to neuronal differentiation, mostly using zebrafish and chick as experimental systems.

Aparicio, Gonzalo Graduate Student Bosch, Santiago Graduate Student Davison, Camilia Graduate Student
Rodao, Magela Graduate Student Veloz, Lucía Graduate Student Licandro, Santiago
Mustto, Lucía

Davison, C., Zolessi, F.R. (2021) Slit2 is necessary for optic axon organization in the zebrafish ventral midline. Cells & development. 166:203677
Aparicio, G., Rodao, M., Badano, J.L., Zolessi, F.R. (2021) Photoreceptor progenitor dynamics in the zebrafish embryo retina and its modulation by primary cilia and N-cadherin. The International journal of developmental biology. 65:439-455
Lepanto, P., Zolessi, F.R., Badano, J.L. (2019) Chapter 5 - Studying Human Genetic Variation in Zebrafish. En: Cellular and Animal Models in Human Genomics Research (Translational and Applied Genomics Series). Elsevier Science. :89-117
Paravani, E.V., Simoniello, M.F., Poletta, G.L., Zolessi, F.R., Casco, V.H. (2018) Cypermethrin: Oxidative stress and genotoxicity in retinal cells of the adult zebrafish. Mutation research. 826:25-32
Álvarez, G., Perdomo, C., Coronel, C., Aguilera, E., Varela, J., Aparicio, G., Zolessi, F.R., Cabrera, N., Vega, C., Rolón, M., Rojas de Arias, A., Pérez-Montfort, R., Cerecetto, H., González, M. (2017) Multi-Anti-Parasitic Activity of Arylidene Ketones and Thiazolidene Hydrazines against Trypanosoma cruzi and Leishmania spp. Molecules. 22(5)
Prieto, D., Zolessi, F.R. (2017) Functional Diversification of the Four MARCKS Family Members in Zebrafish Neural Development. Journal of experimental zoology. Part B, Molecular and developmental evolution. 328(1-2):119-138
Lepanto, P., Davison, C., Casanova, G., Badano, J.L., Zolessi, F.R. (2016) Characterization of primary cilia during the differentiation of retinal ganglion cells in the zebrafish. Neural Development. 11:10
Prieto, D., Aparicio, G., Machado, M., Zolessi, F.R. (2015) Application of the DNA-Specific Stain Methyl Green in the Fluorescent Labeling of Embryos. Journal of visualized experiments : JoVE. (99):e52769
Paolini, A., Duchemin, A.L., Albadri, S., Patzel, E., Bornhorst, D., González Avalos, P., Lemke, S., Machate, A., Brand, M., Sel, S., Di Donato, V., Del Bene, F., Zolessi, F.R., Ramialison, M., Poggi, L. (2015) Asymmetric inheritance of the apical domain and self-renewal of retinal ganglion cell progenitors depend on Anillin function. Development (Cambridge, England). 142(5):832-9
Prieto, D., Aparicio, G., Morande, P.E., Zolessi, F.R. (2014) A fast, low cost, and highly efficient fluorescent DNA labeling method using methyl green. Histochemistry and cell biology. 142:335-345
Randlett, O., Poggi, L., Zolessi, F.R., and Harris, W.A. (2011) The oriented emergence of axons from retinal ganglion cells is directed by laminin contact in vivo. Neuron. 70(2):266-280
Zolessi, F.R., Poggi, L., Wilkinson, C.J., Chien, C.B., and Harris, W.A. (2006) Polarization and orientation of retinal ganglion cells in vivo. Neural Development. 1:2