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Fig. 6

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ZDB-IMAGE-260322-30
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Figures for Bakker-van Bugnum et al., 2026
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Fig. 6

Microscopical analysis of plvapb: EGFP expression in larval brains under hyperglycemic conditions. Representative maximum intensity projection of a confocal z-stack showing Tg(plvapb: EGFP; kdrl: ras-mCherry) zebrafish larvae at 4 dpf (a) and 5 dpf (c) to visualize plvapb: EGFP expression (green) in 0 mM glucose controls, 130 mM mannitol-exposed larvae and after hyperglycemia (130 mM glucose). Vasculature is shown in magenta. Scale bars: 100 μm. Quantification of vessels segments positive for GFP in the brain parenchymal vasculature, indicating PLVAP expression, at 4 dpf (b) and 5 dpf (d).

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