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Publication: Tarahomi et al., 2025 - Transcriptomic identification and developmental mapping of nrg3b expression in zebrafish
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Figure 2

Transcriptomic prioritization of nrg3b in zebrafish. A, PCA of the variance-stabilized RNA-seq data showing clustering of samples mainly based on developmental stages (5, 15, and 30 dpf). Het: Sspo heterozygous mutant, MatZyg: Sspo maternal-zygotic mutant. B, Gene ontology enrichment analysis. C, Coexpression analysis showing high centrality of nrg3b and its connectivity to synaptic genes. D, Variance stabilizing transformation expression pathways for sspo and nrg3b developmental stages in heterozygous (brick) and maternal-zygotic (cyan) embryos. E, Correlation matrix of synaptic and neuronal markers in heterozygous embryos. F, Correlation matrix of synaptic and neuronal markers in maternal-zygotic embryos. Anticorrelation (red), positive correlation (blue).

Acknowledgments

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